Luthra A - Search Results

1

Structural characterization and modeling of the Borrelia burgdorferi hybrid histidine kinase Hk1 periplasmic sensor: A system for sensing small molecules associated with tick feeding.

Bauer WJ, Luthra A, Zhu G, Radolf JD, Malkowski MG, Caimano MJ. Bauer WJ, et al. Among authors: luthra a. J Struct Biol. 2015 Oct;192(1):48-58. doi: 10.1016/j.jsb.2015.08.013. Epub 2015 Aug 28. J Struct Biol. 2015. PMID: 26321039 Free PMC article.

2

PlzA is a bifunctional c-di-GMP biosensor that promotes tick and mammalian host-adaptation of Borrelia burgdorferi.

Groshong AM, Grassmann AA, Luthra A, McLain MA, Provatas AA, Radolf JD, Caimano MJ. Groshong AM, et al. Among authors: luthra a. PLoS Pathog. 2021 Jul 15;17(7):e1009725. doi: 10.1371/journal.ppat.1009725. eCollection 2021 Jul. PLoS Pathog. 2021. PMID: 34265024 Free PMC article.

3

TP0326, a Treponema pallidum β-barrel assembly machinery A (BamA) orthologue and rare outer membrane protein.

Desrosiers DC, Anand A, Luthra A, Dunham-Ems SM, LeDoyt M, Cummings MA, Eshghi A, Cameron CE, Cruz AR, Salazar JC, Caimano MJ, Radolf JD. Desrosiers DC, et al. Among authors: luthra a. Mol Microbiol. 2011 Jun;80(6):1496-515. doi: 10.1111/j.1365-2958.2011.07662.x. Epub 2011 Apr 27. Mol Microbiol. 2011. PMID: 21488980 Free PMC article.

4

The transition from closed to open conformation of Treponema pallidum outer membrane-associated lipoprotein TP0453 involves membrane sensing and integration by two amphipathic helices.

Luthra A, Zhu G, Desrosiers DC, Eggers CH, Mulay V, Anand A, McArthur FA, Romano FB, Caimano MJ, Heuck AP, Malkowski MG, Radolf JD. Luthra A, et al. J Biol Chem. 2011 Dec 2;286(48):41656-41668. doi: 10.1074/jbc.M111.305284. Epub 2011 Sep 29. J Biol Chem. 2011. PMID: 21965687 Free PMC article.

5

The major outer sheath protein (Msp) of Treponema denticola has a bipartite domain architecture and exists as periplasmic and outer membrane-spanning conformers.

Anand A, Luthra A, Edmond ME, Ledoyt M, Caimano MJ, Radolf JD. Anand A, et al. Among authors: luthra a. J Bacteriol. 2013 May;195(9):2060-71. doi: 10.1128/JB.00078-13. Epub 2013 Mar 1. J Bacteriol. 2013. PMID: 23457251 Free PMC article.

6

Structural modeling and physicochemical characterization provide evidence that P66 forms a β-barrel in the Borrelia burgdorferi outer membrane.

Kenedy MR, Luthra A, Anand A, Dunn JP, Radolf JD, Akins DR. Kenedy MR, et al. Among authors: luthra a. J Bacteriol. 2014 Feb;196(4):859-72. doi: 10.1128/JB.01236-13. Epub 2013 Dec 6. J Bacteriol. 2014. PMID: 24317399 Free PMC article.

7

Stage-specific global alterations in the transcriptomes of Lyme disease spirochetes during tick feeding and following mammalian host adaptation.

Iyer R, Caimano MJ, Luthra A, Axline D Jr, Corona A, Iacobas DA, Radolf JD, Schwartz I. Iyer R, et al. Among authors: luthra a. Mol Microbiol. 2015 Feb;95(3):509-38. doi: 10.1111/mmi.12882. Epub 2014 Dec 30. Mol Microbiol. 2015. PMID: 25425211 Free PMC article.

8

Bipartite Topology of Treponema pallidum Repeat Proteins C/D and I: OUTER MEMBRANE INSERTION, TRIMERIZATION, AND PORIN FUNCTION REQUIRE A C-TERMINAL β-BARREL DOMAIN.

Anand A, LeDoyt M, Karanian C, Luthra A, Koszelak-Rosenblum M, Malkowski MG, Puthenveetil R, Vinogradova O, Radolf JD. Anand A, et al. Among authors: luthra a. J Biol Chem. 2015 May 8;290(19):12313-31. doi: 10.1074/jbc.M114.629188. Epub 2015 Mar 24. J Biol Chem. 2015. PMID: 25805501 Free PMC article.

9

A Homology Model Reveals Novel Structural Features and an Immunodominant Surface Loop/Opsonic Target in the Treponema pallidum BamA Ortholog TP_0326.

Luthra A, Anand A, Hawley KL, LeDoyt M, La Vake CJ, Caimano MJ, Cruz AR, Salazar JC, Radolf JD. Luthra A, et al. J Bacteriol. 2015 Jun;197(11):1906-20. doi: 10.1128/JB.00086-15. Epub 2015 Mar 30. J Bacteriol. 2015. PMID: 25825429 Free PMC article.

10

Treponema pallidum in Gel Microdroplets: A Method for Topological Analysis of BamA (TP0326) and Localization of Rare Outer Membrane Proteins.

Luthra A, Anand A, Radolf JD. Luthra A, et al. Methods Mol Biol. 2015;1329:67-75. doi: 10.1007/978-1-4939-2871-2_6. Methods Mol Biol. 2015. PMID: 26427677

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