Lutz JD - Search Results

1

Importance of multi-p450 inhibition in drug-drug interactions: evaluation of incidence, inhibition magnitude, and prediction from in vitro data.

Isoherranen N, Lutz JD, Chung SP, Hachad H, Levy RH, Ragueneau-Majlessi I. Isoherranen N, et al. Among authors: lutz jd. Chem Res Toxicol. 2012 Nov 19;25(11):2285-300. doi: 10.1021/tx300192g. Epub 2012 Sep 27. Chem Res Toxicol. 2012. PMID: 22823924 Free PMC article. Review.

2

Rationalization and prediction of in vivo metabolite exposures: the role of metabolite kinetics, clearance predictions and in vitro parameters.

Lutz JD, Fujioka Y, Isoherranen N. Lutz JD, et al. Expert Opin Drug Metab Toxicol. 2010 Sep;6(9):1095-109. doi: 10.1517/17425255.2010.497487. Expert Opin Drug Metab Toxicol. 2010. PMID: 20557268 Free PMC article. Review.

3

Prediction of relative in vivo metabolite exposure from in vitro data using two model drugs: dextromethorphan and omeprazole.

Lutz JD, Isoherranen N. Lutz JD, et al. Drug Metab Dispos. 2012 Jan;40(1):159-68. doi: 10.1124/dmd.111.042200. Epub 2011 Oct 18. Drug Metab Dispos. 2012. PMID: 22010218 Free PMC article.

4

In vitro-to-in vivo predictions of drug-drug interactions involving multiple reversible inhibitors.

Lutz JD, Isoherranen N. Lutz JD, et al. Expert Opin Drug Metab Toxicol. 2012 Apr;8(4):449-66. doi: 10.1517/17425255.2012.667801. Epub 2012 Mar 3. Expert Opin Drug Metab Toxicol. 2012. PMID: 22384784 Review.

5

Inhibition of CYP2C19 and CYP3A4 by omeprazole metabolites and their contribution to drug-drug interactions.

Shirasaka Y, Sager JE, Lutz JD, Davis C, Isoherranen N. Shirasaka Y, et al. Among authors: lutz jd. Drug Metab Dispos. 2013 Jul;41(7):1414-24. doi: 10.1124/dmd.113.051722. Epub 2013 Apr 25. Drug Metab Dispos. 2013. PMID: 23620487 Free PMC article.

6

Fluoxetine- and norfluoxetine-mediated complex drug-drug interactions: in vitro to in vivo correlation of effects on CYP2D6, CYP2C19, and CYP3A4.

Sager JE, Lutz JD, Foti RS, Davis C, Kunze KL, Isoherranen N. Sager JE, et al. Among authors: lutz jd. Clin Pharmacol Ther. 2014 Jun;95(6):653-62. doi: 10.1038/clpt.2014.50. Epub 2014 Feb 25. Clin Pharmacol Ther. 2014. PMID: 24569517 Free PMC article.

7

Expression and functional characterization of cytochrome P450 26A1, a retinoic acid hydroxylase.

Lutz JD, Dixit V, Yeung CK, Dickmann LJ, Zelter A, Thatcher JE, Nelson WL, Isoherranen N. Lutz JD, et al. Biochem Pharmacol. 2009 Jan 15;77(2):258-68. doi: 10.1016/j.bcp.2008.10.012. Epub 2008 Oct 17. Biochem Pharmacol. 2009. PMID: 18992717 Free PMC article.

8

Stereospecific metabolism of itraconazole by CYP3A4: dioxolane ring scission of azole antifungals.

Peng CC, Shi W, Lutz JD, Kunze KL, Liu JO, Nelson WL, Isoherranen N. Peng CC, et al. Among authors: lutz jd. Drug Metab Dispos. 2012 Mar;40(3):426-35. doi: 10.1124/dmd.111.042739. Epub 2011 Nov 21. Drug Metab Dispos. 2012. PMID: 22106171 Free PMC article.

9

Stereoselective inhibition of CYP2C19 and CYP3A4 by fluoxetine and its metabolite: implications for risk assessment of multiple time-dependent inhibitor systems.

Lutz JD, VandenBrink BM, Babu KN, Nelson WL, Kunze KL, Isoherranen N. Lutz JD, et al. Drug Metab Dispos. 2013 Dec;41(12):2056-65. doi: 10.1124/dmd.113.052639. Epub 2013 Jun 19. Drug Metab Dispos. 2013. PMID: 23785064 Free PMC article.

10

Comparison of the function and expression of CYP26A1 and CYP26B1, the two retinoic acid hydroxylases.

Topletz AR, Thatcher JE, Zelter A, Lutz JD, Tay S, Nelson WL, Isoherranen N. Topletz AR, et al. Among authors: lutz jd. Biochem Pharmacol. 2012 Jan 1;83(1):149-63. doi: 10.1016/j.bcp.2011.10.007. Epub 2011 Oct 14. Biochem Pharmacol. 2012. PMID: 22020119 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

45 results

Search Page

Filters