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Increased susceptibility of human endothelial cells to infections by SARS-CoV-2 variants.
Wagner JUG, Bojkova D, Shumliakivska M, Luxán G, Nicin L, Aslan GS, Milting H, Kandler JD, Dendorfer A, Heumueller AW, Fleming I, Bibli SI, Jakobi T, Dieterich C, Zeiher AM, Ciesek S, Cinatl J, Dimmeler S. Wagner JUG, et al. Among authors: luxan g. Basic Res Cardiol. 2021 Jul 5;116(1):42. doi: 10.1007/s00395-021-00882-8. Basic Res Cardiol. 2021. PMID: 34224022 Free PMC article.
SARS-CoV-2 infects and induces cytotoxic effects in human cardiomyocytes.
Bojkova D, Wagner JUG, Shumliakivska M, Aslan GS, Saleem U, Hansen A, Luxán G, Günther S, Pham MD, Krishnan J, Harter PN, Ermel UH, Frangakis AS, Milting H, Zeiher AM, Klingel K, Cinatl J, Dendorfer A, Eschenhagen T, Tschöpe C, Ciesek S, Dimmeler S. Bojkova D, et al. Among authors: luxan g. Cardiovasc Res. 2020 Dec 1;116(14):2207-2215. doi: 10.1093/cvr/cvaa267. Cardiovasc Res. 2020. PMID: 32966582 Free PMC article.
Single cell sequencing reveals endothelial plasticity with transient mesenchymal activation after myocardial infarction.
Tombor LS, John D, Glaser SF, Luxán G, Forte E, Furtado M, Rosenthal N, Baumgarten N, Schulz MH, Wittig J, Rogg EM, Manavski Y, Fischer A, Muhly-Reinholz M, Klee K, Looso M, Selignow C, Acker T, Bibli SI, Fleming I, Patrick R, Harvey RP, Abplanalp WT, Dimmeler S. Tombor LS, et al. Among authors: luxan g. Nat Commun. 2021 Jan 29;12(1):681. doi: 10.1038/s41467-021-20905-1. Nat Commun. 2021. PMID: 33514719 Free PMC article.
Post-myocardial infarction heart failure dysregulates the bone vascular niche.
Hoffmann J, Luxán G, Abplanalp WT, Glaser SF, Rasper T, Fischer A, Muhly-Reinholz M, Potente M, Assmus B, John D, Zeiher AM, Dimmeler S. Hoffmann J, et al. Among authors: luxan g. Nat Commun. 2021 Jun 25;12(1):3964. doi: 10.1038/s41467-021-24045-4. Nat Commun. 2021. PMID: 34172720 Free PMC article.
Angiotensin II receptor blocker intake associates with reduced markers of inflammatory activation and decreased mortality in patients with cardiovascular comorbidities and COVID-19 disease.
Cremer S, Pilgram L, Berkowitsch A, Stecher M, Rieg S, Shumliakivska M, Bojkova D, Wagner JUG, Aslan GS, Spinner C, Luxán G, Hanses F, Dolff S, Piepel C, Ruppert C, Guenther A, Rüthrich MM, Vehreschild JJ, Wille K, Haselberger M, Heuzeroth H, Hansen A, Eschenhagen T, Cinatl J, Ciesek S, Dimmeler S, Borgmann S, Zeiher A; LEOSS study group. Cremer S, et al. Among authors: luxan g. PLoS One. 2021 Oct 21;16(10):e0258684. doi: 10.1371/journal.pone.0258684. eCollection 2021. PLoS One. 2021. PMID: 34673795 Free PMC article.
The splicing-regulatory lncRNA NTRAS sustains vascular integrity.
Fouani Y, Kirchhof L, Stanicek L, Luxán G, Heumüller AW, Knau A, Fischer A, Devraj K, John D, Neumann P, Bindereif A, Boon RA, Liebner S, Wittig I, Mogler C, Karimova M, Dimmeler S, Jaé N. Fouani Y, et al. Among authors: luxan g. EMBO Rep. 2022 Jun 7;23(6):e54157. doi: 10.15252/embr.202154157. Epub 2022 May 8. EMBO Rep. 2022. PMID: 35527520 Free PMC article.
Aging impairs the neurovascular interface in the heart.
Wagner JUG, Tombor LS, Malacarne PF, Kettenhausen LM, Panthel J, Kujundzic H, Manickam N, Schmitz K, Cipca M, Stilz KA, Fischer A, Muhly-Reinholz M, Abplanalp WT, John D, Mohanta SK, Weber C, Habenicht AJR, Buchmann GK, Angendohr S, Amin E, Scherschel K, Klöcker N, Kelm M, Schüttler D, Clauss S, Günther S, Boettger T, Braun T, Bär C, Pham MD, Krishnan J, Hille S, Müller OJ, Bozoglu T, Kupatt C, Nardini E, Osmanagic-Myers S, Meyer C, Zeiher AM, Brandes RP, Luxán G, Dimmeler S. Wagner JUG, et al. Among authors: luxan g. Science. 2023 Aug 25;381(6660):897-906. doi: 10.1126/science.ade4961. Epub 2023 Aug 24. Science. 2023. PMID: 37616346
26 results