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Systemic delivery of a glucosylceramide synthase inhibitor reduces CNS substrates and increases lifespan in a mouse model of type 2 Gaucher disease.
PLoS One. 2012;7(8):e43310. doi: 10.1371/journal.pone.0043310. Epub 2012 Aug 17.
PLoS One. 2012.
PMID: 22912851
Free PMC article.
α-Galactosidase A knockout mice: progressive organ pathology resembles the type 2 later-onset phenotype of Fabry disease.
Bangari DS, Ashe KM, Desnick RJ, Maloney C, Lydon J, Piepenhagen P, Budman E, Leonard JP, Cheng SH, Marshall J, Thurberg BL.
Bangari DS, et al.
Am J Pathol. 2015 Mar;185(3):651-65. doi: 10.1016/j.ajpath.2014.11.004. Epub 2014 Dec 29.
Am J Pathol. 2015.
PMID: 25553976
Free article.
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A bispecific protein capable of engaging CTLA-4 and MHCII protects non-obese diabetic mice from autoimmune diabetes.
Zhao H, Karman J, Jiang JL, Zhang J, Gumlaw N, Lydon J, Zhou Q, Qiu H, Jiang C, Cheng SH, Zhu Y.
Zhao H, et al.
PLoS One. 2013 May 21;8(5):e63530. doi: 10.1371/journal.pone.0063530. Print 2013.
PLoS One. 2013.
PMID: 23704916
Free PMC article.
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Glomerulopathy in the KK.Cg-A(y) /J mouse reflects the pathology of diabetic nephropathy.
O'Brien SP, Smith M, Ling H, Phillips L, Weber W, Lydon J, Maloney C, Ledbetter S, Arbeeny C, Wawersik S.
O'Brien SP, et al.
J Diabetes Res. 2013;2013:498925. doi: 10.1155/2013/498925. Epub 2013 Apr 24.
J Diabetes Res. 2013.
PMID: 23710468
Free PMC article.
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Biotherapeutic target or sink: analysis of the macrophage mannose receptor tissue distribution in murine models of lysosomal storage diseases.
Zhang XS, Brondyk W, Lydon JT, Thurberg BL, Piepenhagen PA.
Zhang XS, et al. Among authors: lydon jt.
J Inherit Metab Dis. 2011 Jun;34(3):795-809. doi: 10.1007/s10545-011-9285-9. Epub 2011 Mar 17.
J Inherit Metab Dis. 2011.
PMID: 21416197
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