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Preemptive genotyping for personalized medicine: design of the right drug, right dose, right time-using genomic data to individualize treatment protocol.
Bielinski SJ, Olson JE, Pathak J, Weinshilboum RM, Wang L, Lyke KJ, Ryu E, Targonski PV, Van Norstrand MD, Hathcock MA, Takahashi PY, McCormick JB, Johnson KJ, Maschke KJ, Rohrer Vitek CR, Ellingson MS, Wieben ED, Farrugia G, Morrisette JA, Kruckeberg KJ, Bruflat JK, Peterson LM, Blommel JH, Skierka JM, Ferber MJ, Black JL, Baudhuin LM, Klee EW, Ross JL, Veldhuizen TL, Schultz CG, Caraballo PJ, Freimuth RR, Chute CG, Kullo IJ. Bielinski SJ, et al. Among authors: lyke kj. Mayo Clin Proc. 2014 Jan;89(1):25-33. doi: 10.1016/j.mayocp.2013.10.021. Mayo Clin Proc. 2014. PMID: 24388019 Free PMC article.
Acceptability of Electronic Visits for Return of Research Results in the Mayo Clinic Biobank.
Olson JE, Ryu E, Lyke KJ, Bielinski SJ, Winkler EM, Hathcock MA, Bublitz JT, Takahashi PY, Cerhan JR. Olson JE, et al. Among authors: lyke kj. Mayo Clin Proc Innov Qual Outcomes. 2018 Sep 15;2(4):352-358. doi: 10.1016/j.mayocpiqo.2018.07.004. eCollection 2018 Dec. Mayo Clin Proc Innov Qual Outcomes. 2018. PMID: 30560237 Free PMC article.
Synthesis of multi-omic data and community metabolic models reveals insights into the role of hydrogen sulfide in colon cancer.
Hale VL, Jeraldo P, Mundy M, Yao J, Keeney G, Scott N, Cheek EH, Davidson J, Greene M, Martinez C, Lehman J, Pettry C, Reed E, Lyke K, White BA, Diener C, Resendis-Antonio O, Gransee J, Dutta T, Petterson XM, Boardman L, Larson D, Nelson H, Chia N. Hale VL, et al. Methods. 2018 Oct 1;149:59-68. doi: 10.1016/j.ymeth.2018.04.024. Epub 2018 Apr 26. Methods. 2018. PMID: 29704665 Free PMC article.
Distinct microbes, metabolites, and ecologies define the microbiome in deficient and proficient mismatch repair colorectal cancers.
Hale VL, Jeraldo P, Chen J, Mundy M, Yao J, Priya S, Keeney G, Lyke K, Ridlon J, White BA, French AJ, Thibodeau SN, Diener C, Resendis-Antonio O, Gransee J, Dutta T, Petterson XM, Sung J, Blekhman R, Boardman L, Larson D, Nelson H, Chia N. Hale VL, et al. Genome Med. 2018 Oct 31;10(1):78. doi: 10.1186/s13073-018-0586-6. Genome Med. 2018. PMID: 30376889 Free PMC article.