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Page 1
Relevance of the antibody index to diagnose Lyme neuroborreliosis among seropositive patients.
Blanc F, Jaulhac B, Fleury M, de Seze J, de Martino SJ, Remy V, Blaison G, Hansmann Y, Christmann D, Tranchant C. Blanc F, et al. Neurology. 2007 Sep 4;69(10):953-8. doi: 10.1212/01.wnl.0000269672.17807.e0. Neurology. 2007. PMID: 17785663
BACKGROUND: No consensual criteria exist to diagnose neuroborreliosis. The intrathecal anti-Borrelia antibody index (AI) is a necessary criterion to diagnose neuroborreliosis in Europe, but not in the United States. ...However, these studies included only typical cl …
BACKGROUND: No consensual criteria exist to diagnose neuroborreliosis. The intrathecal anti-Borrelia antibody index (AI) is a …
CSF B--lymphocyte chemoattractant (CXCL13) in the early diagnosis of acute Lyme neuroborreliosis.
Ljøstad U, Mygland A. Ljøstad U, et al. J Neurol. 2008 May;255(5):732-7. doi: 10.1007/s00415-008-0785-y. Epub 2008 Mar 17. J Neurol. 2008. PMID: 18344056
An additional control group consisted of 31 patients with multiple sclerosis (MS), 11 with non-inflammatory neurological diseases, and ten with verified non-Lyme meningitis and high CSF cell count. CSF CXCL13 was slightly elevated in 15 MS patients, an …
An additional control group consisted of 31 patients with multiple sclerosis (MS), 11 with non-inflammatory neurological diseases, and ten w …
Relevance of cerebrospinal fluid variables for early diagnosis of neuroborreliosis.
Tumani H, Nölker G, Reiber H. Tumani H, et al. Neurology. 1995 Sep;45(9):1663-70. doi: 10.1212/wnl.45.9.1663. Neurology. 1995. PMID: 7675224
We describe the specificity and sensitivity of measuring a combination of basic CSF variables and Borrelia burgdorferi (Bb)-specific IgG and IgM antibody index (AI) values for the diagnosis of early neuroborreliosis. ...The Bb-specific component of immunog …
We describe the specificity and sensitivity of measuring a combination of basic CSF variables and Borrelia burgdorferi (Bb)-specific …
Cerebrovascular Events in Lyme Neuroborreliosis.
Wittwer B, Pelletier S, Ducrocq X, Maillard L, Mione G, Richard S. Wittwer B, et al. J Stroke Cerebrovasc Dis. 2015 Jul;24(7):1671-8. doi: 10.1016/j.jstrokecerebrovasdis.2015.03.056. Epub 2015 May 20. J Stroke Cerebrovasc Dis. 2015. PMID: 26002071
Cerebral imaging revealed both ischemic (87%) and hemorrhagic lesions (13%) with a multiterritorial aspect in 22% of strokes, and signs of vasculitis in 71%. Analysis of cerebrospinal fluid (CSF) revealed lymphocytic meningitis in 90% of cases and elevated protein l …
Cerebral imaging revealed both ischemic (87%) and hemorrhagic lesions (13%) with a multiterritorial aspect in 22% of strokes, and signs of v …
Cerebrospinal fluid findings in adults with acute Lyme neuroborreliosis.
Djukic M, Schmidt-Samoa C, Lange P, Spreer A, Neubieser K, Eiffert H, Nau R, Schmidt H. Djukic M, et al. J Neurol. 2012 Apr;259(4):630-6. doi: 10.1007/s00415-011-6221-8. Epub 2011 Sep 6. J Neurol. 2012. PMID: 21898139 Free PMC article.
Presence of BB-specific antibodies in the cerebrospinal fluid (CSF) with evidence of their intrathecal production in conjunction with the white cell count in the CSF and typical clinical symptoms is the traditional diagnostic gold standard of Lyme neur …
Presence of BB-specific antibodies in the cerebrospinal fluid (CSF) with evidence of their intrathecal production in conjuncti …
CSF B - lymphocyte chemoattractant (CXCL13) in the early diagnosis of acute Lyme neuroborreliosis.
Ljøstad U, Mygland Å. Ljøstad U, et al. J Neurol. 2008 May;255(5):782. doi: 10.1007/s00415-008-0974-8. Epub 2008 Mar 17. J Neurol. 2008. PMID: 27517589
Eight patients did not fulfil case definitions and were used as controls.At presentation, CSF CXCL13 was elevated in all patients with definite LNB, as compared to a positive CSF B. burgdorferi (Bb) antibody index (AI) in 33 of 37. ...Bb AI was negativ …
Eight patients did not fulfil case definitions and were used as controls.At presentation, CSF CXCL13 was elevated in all patients wit …
[Neurologic and psychiatric manifestations of Lyme disease].
Blanc F; GEBLY. Blanc F, et al. Med Mal Infect. 2007 Jul-Aug;37(7-8):435-45. doi: 10.1016/j.medmal.2006.01.025. Epub 2007 Mar 9. Med Mal Infect. 2007. PMID: 17350199 Review. French.
In endemic areas, Lyme serology must be assessed in case of unexplained neurological or psychiatric disorder. In case of positive serology, CSF assessment with intrathecal anti-Borrelia antibody index will be more efficient to prove the diagnosis....
In endemic areas, Lyme serology must be assessed in case of unexplained neurological or psychiatric disorder. In case of positive ser …
Immunoglobulin abnormalities in cerebrospinal fluid and blood over the course of lymphocytic meningoradiculitis (Bannwarth's syndrome).
Henriksson A, Link H, Cruz M, Stiernstedt G. Henriksson A, et al. Ann Neurol. 1986 Sep;20(3):337-45. doi: 10.1002/ana.410200311. Ann Neurol. 1986. PMID: 3532931
A markedly increased CSF IgM index and an elevated IgG index were observed in all patients during the early phase, reflecting production of these immunoglobulins within the central nervous system. All patients had oligoclonal IgG bands in the CSF …
A markedly increased CSF IgM index and an elevated IgG index were observed in all patients during the early phase, refl …
Lyme Neuroborreliosis With Acute Encephalopathy Despite Early Antibiotic Therapy: A Case Report.
Johannesson JM, Dicks KV, Perkons ME, Cepeda Mora DF, Luedke MW, Ehrlich ME, Houk JL, McKellar MS. Johannesson JM, et al. Am J Case Rep. 2026 Apr 6;27:e951927. doi: 10.12659/AJCR.951927. Am J Case Rep. 2026. PMID: 41941413 Free PMC article.
Lyme neuroborreliosis occurs in up to 15% of untreated Lyme disease cases and most commonly presents with painful radiculitis, cranial nerve palsy, and meningitis; progression to encephalitis occurs in approximately 3.3% to 9% of cases. ...Diagnosis of Lym …
Lyme neuroborreliosis occurs in up to 15% of untreated Lyme disease cases and most commonly presents with painful radiculitis, …
A prospective study on the role of CXCL13 in Lyme neuroborreliosis.
Schmidt C, Plate A, Angele B, Pfister HW, Wick M, Koedel U, Rupprecht TA. Schmidt C, et al. Neurology. 2011 Mar 22;76(12):1051-8. doi: 10.1212/WNL.0b013e318211c39a. Neurology. 2011. PMID: 21422457
BACKGROUND: The definite diagnosis of acute Lyme neuroborreliosis (LNB) requires detection of an increased Borrelia burgdorferi-specific antibody index (AI). ...METHODS: From March 2008 to August 2009, CSF and serum samples from all patients in whom a …
BACKGROUND: The definite diagnosis of acute Lyme neuroborreliosis (LNB) requires detection of an increased Borrelia burgdorferi-speci …
19 results