Lymperopoulos A - Search Results

1

Adrenal GRK2 upregulation mediates sympathetic overdrive in heart failure.

Lymperopoulos A, Rengo G, Funakoshi H, Eckhart AD, Koch WJ. Lymperopoulos A, et al. Nat Med. 2007 Mar;13(3):315-23. doi: 10.1038/nm1553. Epub 2007 Feb 18. Nat Med. 2007. PMID: 17322894

2

Adrenal adrenoceptors in heart failure: fine-tuning cardiac stimulation.

Lymperopoulos A, Rengo G, Koch WJ. Lymperopoulos A, et al. Trends Mol Med. 2007 Dec;13(12):503-11. doi: 10.1016/j.molmed.2007.10.005. Epub 2007 Nov 5. Trends Mol Med. 2007. PMID: 17981507 Review.

3

Modulation of adrenal catecholamine secretion by in vivo gene transfer and manipulation of G protein-coupled receptor kinase-2 activity.

Lymperopoulos A, Rengo G, Zincarelli C, Soltys S, Koch WJ. Lymperopoulos A, et al. Mol Ther. 2008 Feb;16(2):302-7. doi: 10.1038/sj.mt.6300371. Epub 2007 Nov 27. Mol Ther. 2008. PMID: 18223549 Free article.

4

Myocardial adeno-associated virus serotype 6-betaARKct gene therapy improves cardiac function and normalizes the neurohormonal axis in chronic heart failure.

Rengo G, Lymperopoulos A, Zincarelli C, Donniacuo M, Soltys S, Rabinowitz JE, Koch WJ. Rengo G, et al. Among authors: lymperopoulos a. Circulation. 2009 Jan 6;119(1):89-98. doi: 10.1161/CIRCULATIONAHA.108.803999. Epub 2008 Dec 22. Circulation. 2009. PMID: 19103992 Free PMC article.

5

GRK2 as a novel gene therapy target in heart failure.

Rengo G, Lymperopoulos A, Leosco D, Koch WJ. Rengo G, et al. Among authors: lymperopoulos a. J Mol Cell Cardiol. 2011 May;50(5):785-92. doi: 10.1016/j.yjmcc.2010.08.014. Epub 2010 Aug 25. J Mol Cell Cardiol. 2011. PMID: 20800067 Free PMC article. Review.

6

An adrenal beta-arrestin 1-mediated signaling pathway underlies angiotensin II-induced aldosterone production in vitro and in vivo.

Lymperopoulos A, Rengo G, Zincarelli C, Kim J, Soltys S, Koch WJ. Lymperopoulos A, et al. Proc Natl Acad Sci U S A. 2009 Apr 7;106(14):5825-30. doi: 10.1073/pnas.0811706106. Epub 2009 Mar 16. Proc Natl Acad Sci U S A. 2009. PMID: 19289825 Free PMC article.

7

Adrenal GRK2 lowering is an underlying mechanism for the beneficial sympathetic effects of exercise training in heart failure.

Rengo G, Leosco D, Zincarelli C, Marchese M, Corbi G, Liccardo D, Filippelli A, Ferrara N, Lisanti MP, Koch WJ, Lymperopoulos A. Rengo G, et al. Among authors: lymperopoulos a. Am J Physiol Heart Circ Physiol. 2010 Jun;298(6):H2032-8. doi: 10.1152/ajpheart.00702.2009. Epub 2010 Mar 19. Am J Physiol Heart Circ Physiol. 2010. PMID: 20304818 Free article.

8

Reduction of sympathetic activity via adrenal-targeted GRK2 gene deletion attenuates heart failure progression and improves cardiac function after myocardial infarction.

Lymperopoulos A, Rengo G, Gao E, Ebert SN, Dorn GW 2nd, Koch WJ. Lymperopoulos A, et al. J Biol Chem. 2010 May 21;285(21):16378-86. doi: 10.1074/jbc.M109.077859. Epub 2010 Mar 29. J Biol Chem. 2010. PMID: 20351116 Free PMC article.

9

Adrenal beta-arrestin 1 inhibition in vivo attenuates post-myocardial infarction progression to heart failure and adverse remodeling via reduction of circulating aldosterone levels.

Lymperopoulos A, Rengo G, Zincarelli C, Kim J, Koch WJ. Lymperopoulos A, et al. J Am Coll Cardiol. 2011 Jan 18;57(3):356-65. doi: 10.1016/j.jacc.2010.08.635. J Am Coll Cardiol. 2011. PMID: 21232674 Free PMC article.

10

Caveolin-1 deficiency exacerbates cardiac dysfunction and reduces survival in mice with myocardial infarction.

Jasmin JF, Rengo G, Lymperopoulos A, Gupta R, Eaton GJ, Quann K, Gonzales DM, Mercier I, Koch WJ, Lisanti MP. Jasmin JF, et al. Among authors: lymperopoulos a. Am J Physiol Heart Circ Physiol. 2011 Apr;300(4):H1274-81. doi: 10.1152/ajpheart.01173.2010. Epub 2011 Feb 4. Am J Physiol Heart Circ Physiol. 2011. PMID: 21297026 Free PMC article.

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