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TRAIL: a molecule with multiple receptors and control mechanisms.
Griffith TS, Lynch DH. Griffith TS, et al. Curr Opin Immunol. 1998 Oct;10(5):559-63. doi: 10.1016/s0952-7915(98)80224-0. Curr Opin Immunol. 1998. PMID: 9794836 Review.
4-1BB-specific monoclonal antibody promotes the generation of tumor-specific immune responses by direct activation of CD8 T cells in a CD40-dependent manner.
Miller RE, Jones J, Le T, Whitmore J, Boiani N, Gliniak B, Lynch DH. Miller RE, et al. J Immunol. 2002 Aug 15;169(4):1792-800. doi: 10.4049/jimmunol.169.4.1792. J Immunol. 2002. PMID: 12165501
Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo.
Walczak H, Miller RE, Ariail K, Gliniak B, Griffith TS, Kubin M, Chin W, Jones J, Woodward A, Le T, Smith C, Smolak P, Goodwin RG, Rauch CT, Schuh JC, Lynch DH. Walczak H, et al. Nat Med. 1999 Feb;5(2):157-63. doi: 10.1038/5517. Nat Med. 1999. PMID: 9930862
FasL/Fas and TNF/TNFR interactions in the regulation of immune responses and disease.
Lynch DH, Campbell KA, Miller RE, Badley AD, Paya CV. Lynch DH, et al. Behring Inst Mitt. 1996 Oct;(97):175-84. Behring Inst Mitt. 1996. PMID: 8950475 Review. No abstract available.
The role of FasL and TNF in the homeostatic regulation of immune responses.
Lynch DH. Lynch DH. Adv Exp Med Biol. 1996;406:135-8. doi: 10.1007/978-1-4899-0274-0_14. Adv Exp Med Biol. 1996. PMID: 8910679 Review. No abstract available.
The mouse Fas-ligand gene is mutated in gld mice and is part of a TNF family gene cluster.
Lynch DH, Watson ML, Alderson MR, Baum PR, Miller RE, Tough T, Gibson M, Davis-Smith T, Smith CA, Hunter K, et al. Lynch DH, et al. Immunity. 1994 May;1(2):131-6. doi: 10.1016/1074-7613(94)90106-6. Immunity. 1994. PMID: 7889405
Polyethylene glycol-modified GM-CSF expands CD11b(high)CD11c(high) but notCD11b(low)CD11c(high) murine dendritic cells in vivo: a comparative analysis with Flt3 ligand.
Daro E, Pulendran B, Brasel K, Teepe M, Pettit D, Lynch DH, Vremec D, Robb L, Shortman K, McKenna HJ, Maliszewski CR, Maraskovsky E. Daro E, et al. J Immunol. 2000 Jul 1;165(1):49-58. doi: 10.4049/jimmunol.165.1.49. J Immunol. 2000. PMID: 10861034
Intracellular regulation of TRAIL-induced apoptosis in human melanoma cells.
Griffith TS, Chin WA, Jackson GC, Lynch DH, Kubin MZ. Griffith TS, et al. J Immunol. 1998 Sep 15;161(6):2833-40. J Immunol. 1998. PMID: 9743343
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