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Overexpression and deletion of phospholipid transfer protein reduce HDL mass and cholesterol efflux capacity but not macrophage reverse cholesterol transport.
Kuwano T, Bi X, Cipollari E, Yasuda T, Lagor WR, Szapary HJ, Tohyama J, Millar JS, Billheimer JT, Lyssenko NN, Rader DJ. Kuwano T, et al. Among authors: lyssenko nn. J Lipid Res. 2017 Apr;58(4):731-741. doi: 10.1194/jlr.M074625. Epub 2017 Jan 30. J Lipid Res. 2017. PMID: 28137768 Free PMC article.
Cell lipid metabolism modulators 2-bromopalmitate, D609, monensin, U18666A and probucol shift discoidal HDL formation to the smaller-sized particles: implications for the mechanism of HDL assembly.
Quach D, Vitali C, La FM, Xiao AX, Millar JS, Tang C, Rader DJ, Phillips MC, Lyssenko NN. Quach D, et al. Among authors: lyssenko nn. Biochim Biophys Acta. 2016 Dec;1861(12 Pt A):1968-1979. doi: 10.1016/j.bbalip.2016.09.017. Epub 2016 Sep 24. Biochim Biophys Acta. 2016. PMID: 27671775
ATP-Binding Cassette Transporter A1 Deficiency in Human Induced Pluripotent Stem Cell-Derived Hepatocytes Abrogates HDL Biogenesis and Enhances Triglyceride Secretion.
Bi X, Pashos EE, Cuchel M, Lyssenko NN, Hernandez M, Picataggi A, McParland J, Yang W, Liu Y, Yan R, Yu C, DerOhannessian SL, Phillips MC, Morrisey EE, Duncan SA, Rader DJ. Bi X, et al. Among authors: lyssenko nn. EBioMedicine. 2017 Apr;18:139-145. doi: 10.1016/j.ebiom.2017.03.018. Epub 2017 Mar 14. EBioMedicine. 2017. PMID: 28330813 Free PMC article.
Correlates and Predictors of Cerebrospinal Fluid Cholesterol Efflux Capacity from Neural Cells, a Family of Biomarkers for Cholesterol Epidemiology in Alzheimer's Disease.
Cipollari E, Szapary HJ, Picataggi A, Billheimer JT, Lyssenko CA, Ying GS, Shaw LM, Kling MA, Kaddurah-Daouk R, Rader DJ, Praticò D, Lyssenko NN; Alzheimer’s Disease Metabolomics Consortium. Cipollari E, et al. Among authors: lyssenko nn. J Alzheimers Dis. 2020;74(2):563-578. doi: 10.3233/JAD-191246. J Alzheimers Dis. 2020. PMID: 32065798 Free PMC article.
Specificity of ABCA7-mediated cell lipid efflux.
Picataggi A, Rodrigues A, Cromley DA, Wang H, Wiener JP, Garliyev V, Billheimer JT, Grabiner BC, Hurt JA, Chen AC, Han X, Rader DJ, Praticò D, Lyssenko NN. Picataggi A, et al. Among authors: lyssenko nn. Biochim Biophys Acta Mol Cell Biol Lipids. 2022 Jul;1867(7):159157. doi: 10.1016/j.bbalip.2022.159157. Epub 2022 Apr 3. Biochim Biophys Acta Mol Cell Biol Lipids. 2022. PMID: 35381375 Free PMC article.
ApoJ/Clusterin concentrations are determinants of cerebrospinal fluid cholesterol efflux capacity and reduced levels are associated with Alzheimer's disease.
Ko YA, Billheimer JT, Lyssenko NN, Kueider-Paisley A, Wolk DA, Arnold SE, Leung YY, Shaw LM, Trojanowski JQ, Kaddurah-Daouk RF, Kling MA, Rader DJ. Ko YA, et al. Among authors: lyssenko nn. Alzheimers Res Ther. 2022 Dec 26;14(1):194. doi: 10.1186/s13195-022-01119-z. Alzheimers Res Ther. 2022. PMID: 36572909 Free PMC article.
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