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p90 ribosomal S6 kinase 2 promotes invasion and metastasis of human head and neck squamous cell carcinoma cells.
Kang S, Elf S, Lythgoe K, Hitosugi T, Taunton J, Zhou W, Xiong L, Wang D, Muller S, Fan S, Sun SY, Marcus AI, Gu TL, Polakiewicz RD, Chen ZG, Khuri FR, Shin DM, Chen J. Kang S, et al. Among authors: lythgoe k. J Clin Invest. 2010 Apr;120(4):1165-77. doi: 10.1172/JCI40582. Epub 2010 Mar 15. J Clin Invest. 2010. PMID: 20234090 Free PMC article.
Fibroblast growth factor receptor 3 associates with and tyrosine phosphorylates p90 RSK2, leading to RSK2 activation that mediates hematopoietic transformation.
Kang S, Elf S, Dong S, Hitosugi T, Lythgoe K, Guo A, Ruan H, Lonial S, Khoury HJ, Williams IR, Lee BH, Roesel JL, Karsenty G, Hanauer A, Taunton J, Boggon TJ, Gu TL, Chen J. Kang S, et al. Among authors: lythgoe k. Mol Cell Biol. 2009 Apr;29(8):2105-17. doi: 10.1128/MCB.00998-08. Epub 2009 Feb 17. Mol Cell Biol. 2009. PMID: 19223461 Free PMC article.
Tyrosine phosphorylation inhibits PKM2 to promote the Warburg effect and tumor growth.
Hitosugi T, Kang S, Vander Heiden MG, Chung TW, Elf S, Lythgoe K, Dong S, Lonial S, Wang X, Chen GZ, Xie J, Gu TL, Polakiewicz RD, Roesel JL, Boggon TJ, Khuri FR, Gilliland DG, Cantley LC, Kaufman J, Chen J. Hitosugi T, et al. Among authors: lythgoe k. Sci Signal. 2009 Nov 17;2(97):ra73. doi: 10.1126/scisignal.2000431. Sci Signal. 2009. PMID: 19920251 Free PMC article.
Prevalence of persistent SARS-CoV-2 in a large community surveillance study.
Ghafari M, Hall M, Golubchik T, Ayoubkhani D, House T, MacIntyre-Cockett G, Fryer HR, Thomson L, Nurtay A, Kemp SA, Ferretti L, Buck D, Green A, Trebes A, Piazza P, Lonie LJ, Studley R, Rourke E, Smith DL, Bashton M, Nelson A, Crown M, McCann C, Young GR, Santos RAND, Richards Z, Tariq MA, Cahuantzi R; Wellcome Sanger Institute COVID-19 Surveillance Team; COVID-19 Infection Survey Group; COVID-19 Genomics UK (COG-UK) Consortium; Barrett J, Fraser C, Bonsall D, Walker AS, Lythgoe K. Ghafari M, et al. Among authors: lythgoe k. Nature. 2024 Feb;626(8001):1094-1101. doi: 10.1038/s41586-024-07029-4. Epub 2024 Feb 21. Nature. 2024. PMID: 38383783 Free PMC article.
Lineage replacement and evolution captured by 3 years of the United Kingdom Coronavirus (COVID-19) Infection Survey.
Lythgoe KA, Golubchik T, Hall M, House T, Cahuantzi R, MacIntyre-Cockett G, Fryer H, Thomson L, Nurtay A, Ghafani M, Buck D, Green A, Trebes A, Piazza P, Lonie LJ, Studley R, Rourke E, Smith D, Bashton M, Nelson A, Crown M, McCann C, Young GR, Andre Nunes Dos Santos R, Richards Z, Tariq A; Wellcome Sanger Institute COVID-19 Surveillance Team; COVID-19 Infection Survey Group, The COVID-19 Genomics UK (COG-UK) Consortium; Fraser C, Diamond I, Barrett J, Walker AS, Bonsall D. Lythgoe KA, et al. Proc Biol Sci. 2023 Oct 25;290(2009):20231284. doi: 10.1098/rspb.2023.1284. Epub 2023 Oct 18. Proc Biol Sci. 2023. PMID: 37848057 Free PMC article.
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