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The translational oscillation in oocyte and early embryo development.
Iyyappan R, Aleshkina D, Ming H, Dvoran M, Kakavand K, Jansova D, Del Llano E, Gahurova L, Bruce AW, Masek T, Pospisek M, Horvat F, Kubelka M, Jiang Z, Susor A. Iyyappan R, et al. Among authors: pospisek m. Nucleic Acids Res. 2023 Dec 11;51(22):12076-12091. doi: 10.1093/nar/gkad996. Nucleic Acids Res. 2023. PMID: 37950888 Free PMC article.
Acquired data showed significant and uniform activation of key translational initiation and elongation axes specific to M-phases. Although global protein synthesis decreases in M-phases, translation initiation and elongation activity increases in a uniformly fluctua …
Acquired data showed significant and uniform activation of key translational initiation and elongation axes specific to M-phases. Alt …
Vaccinia virus mRNAs containing long 5'-poly(A)-leaders lack a canonical 5'-methylguanosine cap.
Vopálenský V, Sýkora M, Mělková Z, Barvík I, Horáčková K, Mašek T, Pospíšek M. Vopálenský V, et al. Among authors: pospisek m. Nat Commun. 2025 Dec 22;16(1):11340. doi: 10.1038/s41467-025-67916-w. Nat Commun. 2025. PMID: 41430051 Free PMC article.
Our results demonstrate that VACV mRNAs containing long nontemplated 5' poly(A) leaders lack the 5' cap structure in vivo. The probability of the m(7)G cap occurrence decreases with the increasing number of nontemplated adenosines in the 5' poly(A) leader. Although half of …
Our results demonstrate that VACV mRNAs containing long nontemplated 5' poly(A) leaders lack the 5' cap structure in vivo. The probability o …
Ambiguous decoding of the CUG codon alters the functionality of the Candida albicans translation initiation factor 4E.
Feketová Z, Masek T, Vopálenský V, Pospísek M. Feketová Z, et al. Among authors: pospisek m. FEMS Yeast Res. 2010 Aug 1;10(5):558-69. doi: 10.1111/j.1567-1364.2010.00629.x. Epub 2010 Apr 7. FEMS Yeast Res. 2010. PMID: 20491942
As a part of the translational machinery, it plays a key role in the recruitment of mRNA via binding to its m(7)GpppN 5' terminal cap structure. The opportunistic human pathogen Candida albicans is the only known eukaryotic organism with the ability to survive defects in m …
As a part of the translational machinery, it plays a key role in the recruitment of mRNA via binding to its m(7)GpppN 5' terminal cap …