Conformational states of a bacterial α2-macroglobulin resemble those of human complement C3.
Neves D, Estrozi LF, Job V, Gabel F, Schoehn G, Dessen A.
Neves D, et al.
PLoS One. 2012;7(4):e35384. doi: 10.1371/journal.pone.0035384. Epub 2012 Apr 17.
PLoS One. 2012.
PMID: 22530012
Free PMC article.
Notably, alpha(2)Ms are part of a larger protein superfamily that includes proteins of the complement system, such as C3, a multi-domain macromolecule which is also characterized by an internal thioester-carrying domain and whose activation represents the pivotal step in the comp …
Notably, alpha(2)Ms are part of a larger protein superfamily that includes proteins of the complement system, such as C3, a multi-domain mac …