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Ultrafiltration with size-exclusion liquid chromatography for high yield isolation of extracellular vesicles preserving intact biophysical and functional properties.
Nordin JZ, Lee Y, Vader P, Mäger I, Johansson HJ, Heusermann W, Wiklander OP, Hällbrink M, Seow Y, Bultema JJ, Gilthorpe J, Davies T, Fairchild PJ, Gabrielsson S, Meisner-Kober NC, Lehtiö J, Smith CI, Wood MJ, El Andaloussi S. Nordin JZ, et al. Among authors: mager i. Nanomedicine. 2015 May;11(4):879-83. doi: 10.1016/j.nano.2015.01.003. Epub 2015 Feb 4. Nanomedicine. 2015. PMID: 25659648 Free article.
Design of a peptide-based vector, PepFect6, for efficient delivery of siRNA in cell culture and systemically in vivo.
Andaloussi SE, Lehto T, Mäger I, Rosenthal-Aizman K, Oprea II, Simonson OE, Sork H, Ezzat K, Copolovici DM, Kurrikoff K, Viola JR, Zaghloul EM, Sillard R, Johansson HJ, Said Hassane F, Guterstam P, Suhorutšenko J, Moreno PM, Oskolkov N, Hälldin J, Tedebark U, Metspalu A, Lebleu B, Lehtiö J, Smith CI, Langel U. Andaloussi SE, et al. Among authors: mager i. Nucleic Acids Res. 2011 May;39(9):3972-87. doi: 10.1093/nar/gkq1299. Epub 2011 Jan 17. Nucleic Acids Res. 2011. PMID: 21245043 Free PMC article.
Exosomes for targeted siRNA delivery across biological barriers.
El Andaloussi S, Lakhal S, Mäger I, Wood MJ. El Andaloussi S, et al. Among authors: mager i. Adv Drug Deliv Rev. 2013 Mar;65(3):391-7. doi: 10.1016/j.addr.2012.08.008. Epub 2012 Aug 18. Adv Drug Deliv Rev. 2013. PMID: 22921840 Review.
Extracellular vesicle in vivo biodistribution is determined by cell source, route of administration and targeting.
Wiklander OP, Nordin JZ, O'Loughlin A, Gustafsson Y, Corso G, Mäger I, Vader P, Lee Y, Sork H, Seow Y, Heldring N, Alvarez-Erviti L, Smith CI, Le Blanc K, Macchiarini P, Jungebluth P, Wood MJ, Andaloussi SE. Wiklander OP, et al. Among authors: mager i. J Extracell Vesicles. 2015 Apr 20;4:26316. doi: 10.3402/jev.v4.26316. eCollection 2015. J Extracell Vesicles. 2015. PMID: 25899407 Free PMC article.
67 results