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Generation of Gastrointestinal Organoids from Human Pluripotent Stem Cells.
Múnera JO, Wells JM. Múnera JO, et al. Methods Mol Biol. 2017;1597:167-177. doi: 10.1007/978-1-4939-6949-4_12. Methods Mol Biol. 2017. PMID: 28361317
An in vivo model of human small intestine using pluripotent stem cells.
Watson CL, Mahe MM, Múnera J, Howell JC, Sundaram N, Poling HM, Schweitzer JI, Vallance JE, Mayhew CN, Sun Y, Grabowski G, Finkbeiner SR, Spence JR, Shroyer NF, Wells JM, Helmrath MA. Watson CL, et al. Nat Med. 2014 Nov;20(11):1310-4. doi: 10.1038/nm.3737. Epub 2014 Oct 19. Nat Med. 2014. PMID: 25326803 Free PMC article.
A process engineering approach to increase organoid yield.
Arora N, Imran Alsous J, Guggenheim JW, Mak M, Munera J, Wells JM, Kamm RD, Asada HH, Shvartsman SY, Griffith LG. Arora N, et al. Development. 2017 Mar 15;144(6):1128-1136. doi: 10.1242/dev.142919. Epub 2017 Feb 7. Development. 2017. PMID: 28174251 Free PMC article.
Differentiation of Human Pluripotent Stem Cells into Colonic Organoids via Transient Activation of BMP Signaling.
Múnera JO, Sundaram N, Rankin SA, Hill D, Watson C, Mahe M, Vallance JE, Shroyer NF, Sinagoga KL, Zarzoso-Lacoste A, Hudson JR, Howell JC, Chatuvedi P, Spence JR, Shannon JM, Zorn AM, Helmrath MA, Wells JM. Múnera JO, et al. Cell Stem Cell. 2017 Jul 6;21(1):51-64.e6. doi: 10.1016/j.stem.2017.05.020. Epub 2017 Jun 22. Cell Stem Cell. 2017. PMID: 28648364 Free PMC article.
Deriving functional human enteroendocrine cells from pluripotent stem cells.
Sinagoga KL, McCauley HA, Múnera JO, Reynolds NA, Enriquez JR, Watson C, Yang HC, Helmrath MA, Wells JM. Sinagoga KL, et al. Among authors: munera jo. Development. 2018 Oct 1;145(19):dev165795. doi: 10.1242/dev.165795. Development. 2018. PMID: 30143540 Free PMC article.
Activation of Hedgehog Signaling Promotes Development of Mouse and Human Enteric Neural Crest Cells, Based on Single-Cell Transcriptome Analyses.
Lau ST, Li Z, Pui-Ling Lai F, Nga-Chu Lui K, Li P, Munera JO, Pan G, Mahe MM, Hui CC, Wells JM, Ngan ES. Lau ST, et al. Among authors: munera jo. Gastroenterology. 2019 Dec;157(6):1556-1571.e5. doi: 10.1053/j.gastro.2019.08.019. Epub 2019 Aug 20. Gastroenterology. 2019. PMID: 31442438
Insights Into Human Development and Disease From Human Pluripotent Stem Cell Derived Intestinal Organoids.
Daoud A, Múnera JO. Daoud A, et al. Among authors: munera jo. Front Med (Lausanne). 2019 Dec 17;6:297. doi: 10.3389/fmed.2019.00297. eCollection 2019. Front Med (Lausanne). 2019. PMID: 31956653 Free PMC article. Review.
Generation of human colonic organoids from human pluripotent stem cells.
Daoud A, Múnera JO. Daoud A, et al. Among authors: munera jo. Methods Cell Biol. 2020;159:201-227. doi: 10.1016/bs.mcb.2020.03.001. Epub 2020 Apr 8. Methods Cell Biol. 2020. PMID: 32586443
Ets2 regulates colonic stem cells and sensitivity to tumorigenesis.
Múnera J, Ceceña G, Jedlicka P, Wankell M, Oshima RG. Múnera J, et al. Stem Cells. 2011 Mar;29(3):430-9. doi: 10.1002/stem.599. Stem Cells. 2011. PMID: 21425406 Free PMC article.
Differentiation of Human Pluripotent Stem Cells into Colonic Organoids via Transient Activation of BMP Signaling.
Múnera JO, Sundaram N, Rankin SA, Hill D, Watson C, Mahe M, Vallance JE, Shroyer NF, Sinagoga KL, Zarzoso-Lacoste A, Hudson JR, Howell JC, Chatuvedi P, Spence JR, Shannon JM, Zorn AM, Helmrath MA, Wells JM. Múnera JO, et al. Cell Stem Cell. 2019 May 2;24(5):829. doi: 10.1016/j.stem.2019.04.002. Cell Stem Cell. 2019. PMID: 31051135 Free PMC article. No abstract available.
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