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Carbonic anhydrase inhibitors. The beta-carbonic anhydrases from the fungal pathogens Cryptococcus neoformans and Candida albicans are strongly inhibited by substituted-phenyl-1H-indole-5-sulfonamides.
Güzel O, Maresca A, Hall RA, Scozzafava A, Mastrolorenzo A, Mühlschlegel FA, Supuran CT. Güzel O, et al. Among authors: muhlschlegel fa. Bioorg Med Chem Lett. 2010 Apr 15;20(8):2508-11. doi: 10.1016/j.bmcl.2010.02.103. Epub 2010 Mar 3. Bioorg Med Chem Lett. 2010. PMID: 20299219
Carbonic anhydrase inhibitors. Inhibition of the β-class enzymes from the fungal pathogens Candida albicans and Cryptococcus neoformans with branched aliphatic/aromatic carboxylates and their derivatives.
Carta F, Innocenti A, Hall RA, Mühlschlegel FA, Scozzafava A, Supuran CT. Carta F, et al. Among authors: muhlschlegel fa. Bioorg Med Chem Lett. 2011 Apr 15;21(8):2521-6. doi: 10.1016/j.bmcl.2011.02.057. Epub 2011 Feb 17. Bioorg Med Chem Lett. 2011. PMID: 21402476
74 results