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Concerted action of the FasL/Fas and perforin/granzyme A and B pathways is mandatory for the development of early viral hepatitis but not for recovery from viral infection.
Balkow S, Kersten A, Tran TT, Stehle T, Grosse P, Museteanu C, Utermöhlen O, Pircher H, von Weizsäcker F, Wallich R, Müllbacher A, Simon MM. Balkow S, et al. Among authors: mullbacher a. J Virol. 2001 Sep;75(18):8781-91. doi: 10.1128/jvi.75.18.8781-8791.2001. J Virol. 2001. PMID: 11507223 Free PMC article.
Creation of killer poxvirus could have been predicted.
Müllbacher A, Lobigs M. Müllbacher A, et al. J Virol. 2001 Sep;75(18):8353-5. doi: 10.1128/jvi.75.18.8353-8355.2001. J Virol. 2001. PMID: 11507180 Free PMC article. No abstract available.
The flavivirus nonstructural protein NS3 is a dominant source of cytotoxic T cell peptide determinants.
Lobigs M, Arthur CE, Müllbacher A, Blanden RV. Lobigs M, et al. Among authors: mullbacher a. Virology. 1994 Jul;202(1):195-201. doi: 10.1006/viro.1994.1335. Virology. 1994. PMID: 7516597
Interestingly, mapping of cytotoxic T cell antigenic determinants of other flaviviruses also identified the NS3 protein as the dominant source of antigenic peptides (A. B. Hill, A. Mullbacher, C. Parrish, G. Coia, E. G. Westaway, and R. V. Blanden, 1992, J. G …
Interestingly, mapping of cytotoxic T cell antigenic determinants of other flaviviruses also identified the NS3 protein as the dominant sour …
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