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Nucleotide binding triggers a conformational change of the CBS module of the magnesium transporter CNNM2 from a twisted towards a flat structure.
Corral-Rodríguez MÁ, Stuiver M, Abascal-Palacios G, Diercks T, Oyenarte I, Ereño-Orbea J, de Opakua AI, Blanco FJ, Encinar JA, Spiwok V, Terashima H, Accardi A, Müller D, Martínez-Cruz LA. Corral-Rodríguez MÁ, et al. Among authors: muller d. Biochem J. 2014 Nov 15;464(1):23-34. doi: 10.1042/BJ20140409. Biochem J. 2014. PMID: 25184538 Free PMC article.
Purification, crystallization and preliminary crystallographic analysis of the CBS-domain pair of cyclin M2 (CNNM2).
Gómez-García I, Stuiver M, Ereño J, Oyenarte I, Corral-Rodríguez MA, Müller D, Martínez-Cruz LA. Gómez-García I, et al. Among authors: muller d. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Oct 1;68(Pt 10):1198-203. doi: 10.1107/S1744309112035348. Epub 2012 Sep 26. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012. PMID: 23027747 Free PMC article.
Structural Basis of the Oncogenic Interaction of Phosphatase PRL-1 with the Magnesium Transporter CNNM2.
Giménez-Mascarell P, Oyenarte I, Hardy S, Breiderhoff T, Stuiver M, Kostantin E, Diercks T, Pey AL, Ereño-Orbea J, Martínez-Chantar ML, Khalaf-Nazzal R, Claverie-Martin F, Müller D, Tremblay ML, Martínez-Cruz LA. Giménez-Mascarell P, et al. Among authors: muller d. J Biol Chem. 2017 Jan 20;292(3):786-801. doi: 10.1074/jbc.M116.759944. Epub 2016 Nov 29. J Biol Chem. 2017. PMID: 27899452 Free PMC article.
Structural Insights into the Intracellular Region of the Human Magnesium Transport Mediator CNNM4.
Giménez-Mascarell P, Oyenarte I, González-Recio I, Fernández-Rodríguez C, Corral-Rodríguez MÁ, Campos-Zarraga I, Simón J, Kostantin E, Hardy S, Díaz Quintana A, Zubillaga Lizeaga M, Merino N, Diercks T, Blanco FJ, Díaz Moreno I, Martínez-Chantar ML, Tremblay ML, Müller D, Siliqi D, Martínez-Cruz LA. Giménez-Mascarell P, et al. Among authors: muller d. Int J Mol Sci. 2019 Dec 12;20(24):6279. doi: 10.3390/ijms20246279. Int J Mol Sci. 2019. PMID: 31842432 Free PMC article.
Novel Aspects of Renal Magnesium Homeostasis.
Giménez-Mascarell P, Schirrmacher CE, Martínez-Cruz LA, Müller D. Giménez-Mascarell P, et al. Among authors: muller d. Front Pediatr. 2018 Apr 9;6:77. doi: 10.3389/fped.2018.00077. eCollection 2018. Front Pediatr. 2018. PMID: 29686978 Free PMC article. Review.
Current Structural Knowledge on the CNNM Family of Magnesium Transport Mediators.
Giménez-Mascarell P, González-Recio I, Fernández-Rodríguez C, Oyenarte I, Müller D, Martínez-Chantar ML, Martínez-Cruz LA. Giménez-Mascarell P, et al. Among authors: muller d. Int J Mol Sci. 2019 Mar 6;20(5):1135. doi: 10.3390/ijms20051135. Int J Mol Sci. 2019. PMID: 30845649 Free PMC article. Review.
CNNM2, encoding a basolateral protein required for renal Mg2+ handling, is mutated in dominant hypomagnesemia.
Stuiver M, Lainez S, Will C, Terryn S, Günzel D, Debaix H, Sommer K, Kopplin K, Thumfart J, Kampik NB, Querfeld U, Willnow TE, Němec V, Wagner CA, Hoenderop JG, Devuyst O, Knoers NV, Bindels RJ, Meij IC, Müller D. Stuiver M, et al. Among authors: muller d. Am J Hum Genet. 2011 Mar 11;88(3):333-43. doi: 10.1016/j.ajhg.2011.02.005. Am J Hum Genet. 2011. PMID: 21397062 Free PMC article.
The phenotypic and genetic spectrum of patients with heterozygous mutations in cyclin M2 (CNNM2).
Franken GAC, Müller D, Mignot C, Keren B, Lévy J, Tabet AC, Germanaud D, Tejada MI, Kroes HY, Nievelstein RAJ, Brimble E, Ruzhnikov M, Claverie-Martin F, Szczepańska M, Ćuk M, Latta F, Konrad M, Martínez-Cruz LA, Bindels RJM, Hoenderop JGJ, Schlingmann KP, de Baaij JHF. Franken GAC, et al. Among authors: muller d. Hum Mutat. 2021 Apr;42(4):473-486. doi: 10.1002/humu.24182. Epub 2021 Mar 1. Hum Mutat. 2021. PMID: 33600043 Free PMC article.
Membrane topology and intracellular processing of cyclin M2 (CNNM2).
de Baaij JH, Stuiver M, Meij IC, Lainez S, Kopplin K, Venselaar H, Müller D, Bindels RJ, Hoenderop JG. de Baaij JH, et al. Among authors: muller d. J Biol Chem. 2012 Apr 20;287(17):13644-55. doi: 10.1074/jbc.M112.342204. Epub 2012 Mar 7. J Biol Chem. 2012. PMID: 22399287 Free PMC article.
4,867 results