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Leptin acts via leptin receptor-expressing lateral hypothalamic neurons to modulate the mesolimbic dopamine system and suppress feeding.
Leinninger GM, Jo YH, Leshan RL, Louis GW, Yang H, Barrera JG, Wilson H, Opland DM, Faouzi MA, Gong Y, Jones JC, Rhodes CJ, Chua S Jr, Diano S, Horvath TL, Seeley RJ, Becker JB, Münzberg H, Myers MG Jr. Leinninger GM, et al. Among authors: munzberg h. Cell Metab. 2009 Aug;10(2):89-98. doi: 10.1016/j.cmet.2009.06.011. Cell Metab. 2009. PMID: 19656487 Free PMC article.
Leptin receptor action and mechanisms of leptin resistance.
Münzberg H, Björnholm M, Bates SH, Myers MG Jr. Münzberg H, et al. Cell Mol Life Sci. 2005 Mar;62(6):642-52. doi: 10.1007/s00018-004-4432-1. Cell Mol Life Sci. 2005. PMID: 15770417 Free article. Review.
Enhanced PIP3 signaling in POMC neurons causes KATP channel activation and leads to diet-sensitive obesity.
Plum L, Ma X, Hampel B, Balthasar N, Coppari R, Münzberg H, Shanabrough M, Burdakov D, Rother E, Janoschek R, Alber J, Belgardt BF, Koch L, Seibler J, Schwenk F, Fekete C, Suzuki A, Mak TW, Krone W, Horvath TL, Ashcroft FM, Brüning JC. Plum L, et al. Among authors: munzberg h. J Clin Invest. 2006 Jul;116(7):1886-901. doi: 10.1172/JCI27123. Epub 2006 Jun 22. J Clin Invest. 2006. PMID: 16794735 Free PMC article.
Leptin receptor signaling and action in the central nervous system.
Leshan RL, Björnholm M, Münzberg H, Myers MG Jr. Leshan RL, et al. Among authors: munzberg h. Obesity (Silver Spring). 2006 Aug;14 Suppl 5:208S-212S. doi: 10.1038/oby.2006.310. Obesity (Silver Spring). 2006. PMID: 17021368 Free article. Review.
112 results