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1977 1
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Detection of Man5GlcNAc and related free oligomannosides in the cytosol fraction of hen oviduct.
Iwai K, Mega T, Hase S. Iwai K, et al. J Biochem. 1999 Jan;125(1):70-4. doi: 10.1093/oxfordjournals.jbchem.a022270. J Biochem. 1999. PMID: 9880799 Free article.
The presence of free oligomannosides in cytosol has been demonstrated by metabolic radiolabeling, and Manalpha1-2Manalpha1-2Manalpha1-3(Manalpha1-6)++ +Manbeta1-4GlcNAc was detected as the main free oligomannoside in Chinese hamster ovary cells [Kmiecik, D., Herman, V., Stroop, C …
The presence of free oligomannosides in cytosol has been demonstrated by metabolic radiolabeling, and Manalpha1-2Manalpha1-2Manalpha1-3(Mana …
O-linked N-acetylglucosaminyltransferase inhibition prevents G2/M transition in Xenopus laevis oocytes.
Dehennaut V, Lefebvre T, Sellier C, Leroy Y, Gross B, Walker S, Cacan R, Michalski JC, Vilain JP, Bodart JF. Dehennaut V, et al. J Biol Chem. 2007 Apr 27;282(17):12527-36. doi: 10.1074/jbc.M700444200. Epub 2007 Feb 28. J Biol Chem. 2007. PMID: 17329255 Free article.
Progesterone triggers meiotic resumption also called the G(2)/M transition. This event is characterized by germinal vesicle breakdown (GVBD) and by a burst in phosphorylation level that reflects activation of M-phase-promoting factor (MPF) and MAPK pathways. ...To i …
Progesterone triggers meiotic resumption also called the G(2)/M transition. This event is characterized by germinal vesicle breakdown …
Posteromedial geometric parameters associated with ramp lesions in ACL-injured knees.
Kemah B, Cacan MA, Koraman E, Korkmaz O, Erdil ME. Kemah B, et al. Knee. 2026 Jun 6;62:104512. doi: 10.1016/j.knee.2026.104512. Online ahead of print. Knee. 2026. PMID: 42250471 Free article.
Adults with preoperative long-leg radiographs, standardized knee MRI, and arthroscopic confirmation of ramp status were included; those with BMI 30 kg/m(2), prior ipsilateral surgery, revision ACL reconstruction, multiligament injury, periarticular fracture, advanced oste …
Adults with preoperative long-leg radiographs, standardized knee MRI, and arthroscopic confirmation of ramp status were included; those with …
Exploring the TRIM15 protein interaction network as a drug target using machine learning in pancreatic cancer.
Bas Topcu KS, Temiz K, Cacan E. Bas Topcu KS, et al. Discov Oncol. 2025 Nov 26;16(1):2186. doi: 10.1007/s12672-025-03847-8. Discov Oncol. 2025. PMID: 41296246 Free PMC article.
Importin-beta1, which is overexpressed in many cancers, is associated with tumor progression and its inhibitor, importazole, exhibits antitumor activity by inducing G2/M cell cycle arrest and apoptosis. Here, TRIM15 regulation, apoptosis mechanism and immune checkpoint mec …
Importin-beta1, which is overexpressed in many cancers, is associated with tumor progression and its inhibitor, importazole, exhibits antitu …
Neuroprotective and oxidative stress-modulating effects of midazolam, dexmedetomidine and ketamine in a controlled cortical impact model of traumatic brain injury in rats.
Özkan F, Zor S, Çakıllı M, Yılmaz E, Çaçan E. Özkan F, et al. Neurol Res. 2026 Mar 25:1-9. doi: 10.1080/01616412.2026.2650442. Online ahead of print. Neurol Res. 2026. PMID: 41879979
METHODS: Forty adult male rats were randomized into five groups (n = 8): Sham (S), TBI (T), TBI + Dexmedetomidine (D), TBI + Ketamine (K), and TBI + Midazolam (M). TBI was induced using the controlled cortical impact method. Study drugs were administered intraperitoneally …
METHODS: Forty adult male rats were randomized into five groups (n = 8): Sham (S), TBI (T), TBI + Dexmedetomidine (D), TBI + Ketamine (K), a …
Creatinine and hemoglobin/creatinine ratio as predictors of 12-month recurrence after direct visual internal urethrotomy for short-segment (<2 cm) bulbar urethral strictures.
Kayar R, Kayar K, Çaçan H, Tokuc E, Öztürk Mİ. Kayar R, et al. Urologia. 2026 May 4:3915603261447735. doi: 10.1177/03915603261447735. Online ahead of print. Urologia. 2026. PMID: 42080561

Patients with recurrence had higher creatinine (1.10 vs 0.99 mg/dL, p < 0.001), lower eGFR (74.0 vs 88.0 mL/min/1.73 m(2), p < 0.001), and lower Hgb/Cre ratios (12.13 vs 14.28, p = 0.002). Endoscopic surgery-related etiology was strongly associated with recurrence (7

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Patients with recurrence had higher creatinine (1.10 vs 0.99 mg/dL, p < 0.001), lower eGFR (74.0 vs 88.0 mL/min/1.73 m(2), p <

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Effect of cyclic nucleotides in vitro assays of rat liver galactosyltransferase.
Debeire P, Hoflack B, Cacan R, Verbert A, Montreuil J. Debeire P, et al. Biochimie. 1977;59(5-6):473-7. doi: 10.1016/s0300-9084(77)80052-7. Biochimie. 1977. PMID: 196678
An overall stimulation is observed when cAMP or cGMP (concentration higher that 10(-6) M) are added to the incubation medium. However, more detailed experiments show that the cyclic nucleotides do not act as direct effectors of the enzyme but present the precursors degrada …
An overall stimulation is observed when cAMP or cGMP (concentration higher that 10(-6) M) are added to the incubation medium. However …