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A monoterpene, unique component of thyme honeys, induces apoptosis in prostate cancer cells via inhibition of NF-κB activity and IL-6 secretion.
Kassi E, Chinou I, Spilioti E, Tsiapara A, Graikou K, Karabournioti S, Manoussakis M, Moutsatsou P. Kassi E, et al. Among authors: manoussakis m. Phytomedicine. 2014 Sep 25;21(11):1483-9. doi: 10.1016/j.phymed.2014.04.032. Epub 2014 Jun 2. Phytomedicine. 2014. PMID: 24932974
The trihydroxy ketone exerted significant apoptotic activity in PC-3 prostate cancer cells at 100 muM, while it inhibited NF-kappaB phosphorylation and IL-6 secretion at a concentration range 10(-6)-10(-4)M. Akt and JNK signaling were not found to participate in this proce …
The trihydroxy ketone exerted significant apoptotic activity in PC-3 prostate cancer cells at 100 muM, while it inhibited NF-kappaB phosphor …