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PAM-flexible Engineered FnCas9 variants for robust and ultra-precise genome editing and diagnostics.
Acharya S, Ansari AH, Kumar Das P, Hirano S, Aich M, Rauthan R, Mahato S, Maddileti S, Sarkar S, Kumar M, Phutela R, Gulati S, Rahman A, Goel A, Afzal C, Paul D, Agrawal T, Pulimamidi VK, Jalali S, Nishimasu H, Mariappan I, Nureki O, Maiti S, Chakraborty D. Acharya S, et al. Among authors: mariappan i. Nat Commun. 2024 Jun 28;15(1):5471. doi: 10.1038/s41467-024-49233-w. Nat Commun. 2024. PMID: 38942756 Free PMC article.
Practice Patterns and Outcome of Extracorporeal Membrane Oxygenation Therapy for Severe Acute Respiratory Distress Syndrome in Indian ICUs.
Mariappan R, Kumar M, Ramakrishnan N, Mani AK, Kumar S, Chandrasekaran V. Mariappan R, et al. Indian J Crit Care Med. 2021 Nov;25(11):1263-1268. doi: 10.5005/jp-journals-10071-23928. Indian J Crit Care Med. 2021. PMID: 34866823 Free PMC article.
HOW TO CITE THIS ARTICLE: Mariappan R, Kumar M, Ramakrishnan N, Mani AK, Kumar S, Chandrasekaran V. Practice Patterns and Outcome of Extracorporeal Membrane Oxygenation Therapy for Severe Acute Respiratory Distress Syndrome in Indian ICUs. ...
HOW TO CITE THIS ARTICLE: Mariappan R, Kumar M, Ramakrishnan N, Mani AK, Kumar S, Chandrasekaran V. Practice Patterns and Outcome of …
A Murine Model of Vesicant-Induced Acute Lung Injury.
Zafar I, Manzoor S, Mariappan N, Ahmad S, Athar M, Antony V, Ahmad A. Zafar I, et al. Among authors: mariappan n. J Pharmacol Exp Ther. 2024 Jan 17;388(2):568-575. doi: 10.1124/jpet.123.001780. J Pharmacol Exp Ther. 2024. PMID: 38050084 Free PMC article.
Acute pulmonary effects of aerosolized nicotine.
Ahmad S, Zafar I, Mariappan N, Husain M, Wei CC, Vetal N, Eltoum IA, Ahmad A. Ahmad S, et al. Among authors: mariappan n. Am J Physiol Lung Cell Mol Physiol. 2019 Jan 1;316(1):L94-L104. doi: 10.1152/ajplung.00564.2017. Epub 2018 Oct 25. Am J Physiol Lung Cell Mol Physiol. 2019. PMID: 30358437 Free PMC article.
METTL3 stabilization by PIN1 promotes breast tumorigenesis via enhanced m(6)A-dependent translation.
Bhattarai PY, Kim G, Lim SC, Mariappan R, Ohn T, Choi HS. Bhattarai PY, et al. Among authors: mariappan r. Oncogene. 2023 Mar;42(13):1010-1023. doi: 10.1038/s41388-023-02617-6. Epub 2023 Feb 8. Oncogene. 2023. PMID: 36755057
We explored the regulatory roles of peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) in METTL3 stability and m(6)A modification of mRNA. PIN1 interacted with METTL3 and prevented its ubiquitin-dependent proteasomal and lysosomal degradation. It stabilized METT …
We explored the regulatory roles of peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) in METTL3 stability and m(6)A modif …
Plasmid-Mediated Fluoroquinolone Resistance in Pseudomonas aeruginosa and Acinetobacter baumannii.
Venkataramana GP, Lalitha AKV, Mariappan S, Sekar U. Venkataramana GP, et al. Among authors: mariappan s. J Lab Physicians. 2022 Feb 9;14(3):271-277. doi: 10.1055/s-0042-1742636. eCollection 2022 Sep. J Lab Physicians. 2022. PMID: 36119417 Free PMC article.
Efflux pump activity was evaluated using carbonyl-cyanide m-chlorophenylhydrazone (CCCP). The presence of PMQR genes was screened by PCR amplification. ...
Efflux pump activity was evaluated using carbonyl-cyanide m-chlorophenylhydrazone (CCCP). The presence of PMQR genes was screened by …
Association between vision and cognitive function among community-dwelling older adults in Selangor, Malaysia.
Mohammed Z, Kee QT, Fadzil NM, Abd Rahman MH, Din NC, Mariappan V, Shahar S. Mohammed Z, et al. Among authors: mariappan v. Int J Ophthalmol. 2023 Jan 18;16(1):115-120. doi: 10.18240/ijo.2023.01.17. eCollection 2023. Int J Ophthalmol. 2023. PMID: 36659949 Free PMC article.
Global cognitive function was assessed using the Mini-Mental State Examination (M-MSE) and the Malay language version of the Montreal Cognitive Assessment (M-MoCA). ...RESULTS: No significant association was observed between vision and M-MSE and M-MoCA …
Global cognitive function was assessed using the Mini-Mental State Examination (M-MSE) and the Malay language version of the Montreal …
Observations of interventricular septal behavior during left bundle branch pacing.
Ponnusamy SS, Ganesan V, Anand V, Vadivelu R, Kumar M, Mariappan S, Murugan S, Vijayaraman P. Ponnusamy SS, et al. Among authors: mariappan s. J Cardiovasc Electrophysiol. 2023 Nov;34(11):2246-2254. doi: 10.1111/jce.16057. Epub 2023 Sep 11. J Cardiovasc Electrophysiol. 2023. PMID: 37694670
Neither perforation nor further change in premature-ventricular-complex morphology beyond M-beat were observed despite additional few unintentional rotations indicating the protective mechanism of LV-endocardium. ...
Neither perforation nor further change in premature-ventricular-complex morphology beyond M-beat were observed despite additional few …
A Tribute to Professor Saranjit Singh - A Critical Thinker, Innovator, Mentor, and Educator.
Ladumor MK, Paudel A, Modhave D, Sharma S, Balhara A, Singh DK, Ramalingam M, Shah R, Pavankumarraju S, Kurmi M, Mariappan TT, Bhutani H, Prasad B. Ladumor MK, et al. Among authors: mariappan tt. J Pharm Sci. 2022 May;111(5):1224-1231. doi: 10.1016/j.xphs.2021.10.024. Epub 2021 Oct 23. J Pharm Sci. 2022. PMID: 34699842
He has published 250 research articles, reviews, editorials, patent, book, and book chapters, and received numerous awards, including the Professor M.L. Khorana Memorial Lecture Award from the Indian Pharmaceutical Association (IPA) and the Outstanding Analyst and Eminent …
He has published 250 research articles, reviews, editorials, patent, book, and book chapters, and received numerous awards, including the Pr …
Cytotoxic Activity of Isoniazid Derivative in Human Breast Cancer Cells.
Barathan M, Zulpa AK, Vellasamy KM, Mariappan V, Shivashekaregowda NKH, Ibrahim ZA, Vadivelu J. Barathan M, et al. Among authors: mariappan v. In Vivo. 2021 Sep-Oct;35(5):2675-2685. doi: 10.21873/invivo.12551. In Vivo. 2021. PMID: 34410956 Free PMC article.
Apoptosis assay revealed that ITHB4, at a concentration equal to the IC(50), induces apoptosis of MCF-7 cells and cell cycle arrest at the sub-G1 and G(2)/M phases. ITHB4 triggered accumulation of intracellular ROS and nuclear DNA fragmentation. ...
Apoptosis assay revealed that ITHB4, at a concentration equal to the IC(50), induces apoptosis of MCF-7 cells and cell cycle arrest at the s …
57 results