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Transcription Factor MafB Coordinates Epidermal Keratinocyte Differentiation.
Miyai M, Hamada M, Moriguchi T, Hiruma J, Kamitani-Kawamoto A, Watanabe H, Hara-Chikuma M, Takahashi K, Takahashi S, Kataoka K. Miyai M, et al. J Invest Dermatol. 2016 Sep;136(9):1848-1857. doi: 10.1016/j.jid.2016.05.088. Epub 2016 May 18. J Invest Dermatol. 2016. PMID: 27208706 Free article. Review.
We demonstrate that the transcription factor MafB is expressed in differentiating keratinocytes in mice and is transcriptionally upregulated upon human keratinocyte differentiation in vitro. ...Our results indicate that MafB is a component of the gene …
We demonstrate that the transcription factor MafB is expressed in differentiating keratinocytes in mice and is transcriptional …
Ectopic expression of the transcription factor MafB in basal keratinocytes induces hyperproliferation and perturbs epidermal homeostasis.
Miyai M, Tsunekage Y, Saito M, Kohno K, Takahashi K, Kataoka K. Miyai M, et al. Exp Dermatol. 2017 Nov;26(11):1039-1045. doi: 10.1111/exd.13364. Epub 2017 Jul 3. Exp Dermatol. 2017. PMID: 28418611
Recently, MafB was identified as one of the transcription factors that regulate epidermal keratinocyte differentiation. MafB is expressed in postmitotic differentiating keratinocytes, and epidermal differentiation is partially impaired in …
Recently, MafB was identified as one of the transcription factors that regulate epidermal keratinocyte differentiation. …
Expression of c-maf and mafB genes in the skin during rat embryonic development.
Ogata A, Shimizu T, Abe R, Shimizu H, Sakai M. Ogata A, et al. Acta Histochem. 2004 Feb;106(1):65-7. doi: 10.1016/j.acthis.2003.10.001. Acta Histochem. 2004. PMID: 15032330
On ED 19, high expression was detected in the nucleus of basal keratinocytes and developing hair germs. On postnatal day (PD) 3, expression of c-maf had disappeared in epidermis and hair follicles. MafB showed similar expression patterns as c-maf. Our finding …
On ED 19, high expression was detected in the nucleus of basal keratinocytes and developing hair germs. On postnatal day (PD) 3, expr …
C/EBPδ gene targets in human keratinocytes.
Borrelli S, Fanoni D, Dolfini D, Alotto D, Ravo M, Grober OM, Weisz A, Castagnoli C, Berti E, Vigano MA, Mantovani R. Borrelli S, et al. PLoS One. 2010 Nov 2;5(11):e13789. doi: 10.1371/journal.pone.0013789. PLoS One. 2010. PMID: 21072181 Free PMC article.
We identified C/EBPδ target genes in human primary keratinocytes by ChIP on chip and profiling of cells functionally inactivated with siRNA. ...Functional inactivation of C/EBPδ as well as overexpressions of two TF targets--MafB and SOX2--affect expression of marker …
We identified C/EBPδ target genes in human primary keratinocytes by ChIP on chip and profiling of cells functionally inactivated with …
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