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Transcription Factor MafB Coordinates Epidermal Keratinocyte Differentiation.
Miyai M, Hamada M, Moriguchi T, Hiruma J, Kamitani-Kawamoto A, Watanabe H, Hara-Chikuma M, Takahashi K, Takahashi S, Kataoka K. Miyai M, et al. J Invest Dermatol. 2016 Sep;136(9):1848-1857. doi: 10.1016/j.jid.2016.05.088. Epub 2016 May 18. J Invest Dermatol. 2016. PMID: 27208706 Free article. Review.
Mammalian epidermis is a stratified epithelium composed of distinct layers of keratinocytes. ...Our results indicate that MafB is a component of the gene expression program that regulates epidermal keratinocyte differentiation....
Mammalian epidermis is a stratified epithelium composed of distinct layers of keratinocytes. ...Our results indicate that M
Ectopic expression of the transcription factor MafB in basal keratinocytes induces hyperproliferation and perturbs epidermal homeostasis.
Miyai M, Tsunekage Y, Saito M, Kohno K, Takahashi K, Kataoka K. Miyai M, et al. Exp Dermatol. 2017 Nov;26(11):1039-1045. doi: 10.1111/exd.13364. Epub 2017 Jul 3. Exp Dermatol. 2017. PMID: 28418611
Recently, MafB was identified as one of the transcription factors that regulate epidermal keratinocyte differentiation. MafB is expressed in postmitotic differentiating keratinocytes, and epidermal differentiation is partially impaired in …
Recently, MafB was identified as one of the transcription factors that regulate epidermal keratinocyte differentiation. …
Expression of c-maf and mafB genes in the skin during rat embryonic development.
Ogata A, Shimizu T, Abe R, Shimizu H, Sakai M. Ogata A, et al. Acta Histochem. 2004 Feb;106(1):65-7. doi: 10.1016/j.acthis.2003.10.001. Acta Histochem. 2004. PMID: 15032330
On postnatal day (PD) 3, expression of c-maf had disappeared in epidermis and hair follicles. MafB showed similar expression patterns as c-maf. Our findings indicate that c-maf and mafB are involved in embryonic development of epidermis and hair follic …
On postnatal day (PD) 3, expression of c-maf had disappeared in epidermis and hair follicles. MafB showed similar expression p …
C/EBPδ gene targets in human keratinocytes.
Borrelli S, Fanoni D, Dolfini D, Alotto D, Ravo M, Grober OM, Weisz A, Castagnoli C, Berti E, Vigano MA, Mantovani R. Borrelli S, et al. PLoS One. 2010 Nov 2;5(11):e13789. doi: 10.1371/journal.pone.0013789. PLoS One. 2010. PMID: 21072181 Free PMC article.
Functional inactivation of C/EBPdelta as well as overexpressions of two TF targets--MafB and SOX2--affect expression of markers of keratinocyte differentiation. ...Our data indicate that C/EBPdelta plays a role in late stages of keratinocyte differentiation.. …
Functional inactivation of C/EBPdelta as well as overexpressions of two TF targets--MafB and SOX2--affect expression of markers of …