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1996 1
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2003 2
2004 2
2005 5
2006 5
2007 4
2008 2
2009 9
2010 1
2011 8
2012 5
2013 6
2014 8
2015 5
2016 12
2017 13
2018 5
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2020 19
2021 15
2022 5
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126 results
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Page 1
MAFB and MAF Transcription Factors as Macrophage Checkpoints for COVID-19 Severity.
Vega MA, Simón-Fuentes M, González de la Aleja A, Nieto C, Colmenares M, Herrero C, Domínguez-Soto Á, Corbí ÁL. Vega MA, et al. Front Immunol. 2020 Nov 18;11:603507. doi: 10.3389/fimmu.2020.603507. eCollection 2020. Front Immunol. 2020. PMID: 33312178 Free PMC article.
Our proposal stems from the recent identification of pathogenic lung macrophage subsets in severe COVID-19, and takes into consideration the previously reported ability of MAFB to dampen IFN type I production, as well as the critical role of MAFB and MAF in t …
Our proposal stems from the recent identification of pathogenic lung macrophage subsets in severe COVID-19, and takes into considerat …
Lymphatic MAFB regulates vascular patterning during developmental and pathological lymphangiogenesis.
Dieterich LC, Tacconi C, Menzi F, Proulx ST, Kapaklikaya K, Hamada M, Takahashi S, Detmar M. Dieterich LC, et al. Angiogenesis. 2020 Aug;23(3):411-423. doi: 10.1007/s10456-020-09721-1. Epub 2020 Apr 19. Angiogenesis. 2020. PMID: 32307629 Free PMC article.
MAFB is a transcription factor involved in the terminal differentiation of several cell types, including macrophages and keratinocytes. ...However, it has remained unknown whether this effect is LEC-intrinsic and whether MAFB might also be involved in postnat …
MAFB is a transcription factor involved in the terminal differentiation of several cell types, including macrophages and kerat …
Loss of Mafb and Maf distorts myeloid cell ratios and disrupts fetal mouse testis vascularization and organogenesis†.
Li SY, Gu X, Heinrich A, Hurley EG, Capel B, DeFalco T. Li SY, et al. Biol Reprod. 2021 Oct 11;105(4):958-975. doi: 10.1093/biolre/ioab098. Biol Reprod. 2021. PMID: 34007995 Free PMC article.
In general, Mafb and Maf alone were dispensable for gonad development; however, when both genes were deleted, we observed significant defects in testicular morphogenesis, indicating that Mafb and Maf work redundantly during testis differentiation. These results demo …
In general, Mafb and Maf alone were dispensable for gonad development; however, when both genes were deleted, we observed significant …
Aryl Hydrocarbon Receptor Controls Monocyte Differentiation into Dendritic Cells versus Macrophages.
Goudot C, Coillard A, Villani AC, Gueguen P, Cros A, Sarkizova S, Tang-Huau TL, Bohec M, Baulande S, Hacohen N, Amigorena S, Segura E. Goudot C, et al. Immunity. 2017 Sep 19;47(3):582-596.e6. doi: 10.1016/j.immuni.2017.08.016. Immunity. 2017. PMID: 28930664 Free article.
After entering tissues, monocytes differentiate into cells that share functional features with either macrophages or dendritic cells (DCs). How monocyte fate is directed toward monocyte-derived macrophages (mo-Macs) or monocyte-derived DCs (mo-DCs) and which transcr …
After entering tissues, monocytes differentiate into cells that share functional features with either macrophages or dendritic cells …
Constructing a ceRNA-immunoregulatory network associated with the development and prognosis of human atherosclerosis through weighted gene co-expression network analysis.
Liu Y, Liu N, Liu Q. Liu Y, et al. Aging (Albany NY). 2021 Jan 17;13(2):3080-3100. doi: 10.18632/aging.202486. Epub 2021 Jan 17. Aging (Albany NY). 2021. PMID: 33460396 Free PMC article.
CIBERSORT and GSVA were used to calculate the immune cell infiltration score and identified macrophage as hub immunocyte in plaque development. A macrophage related ceRNA subnetwork was constructed through correlation analysis. Samples from Biobank of Karolinska End …
CIBERSORT and GSVA were used to calculate the immune cell infiltration score and identified macrophage as hub immunocyte in plaque de …
Balance of MafB and PU.1 specifies alternative macrophage or dendritic cell fate.
Bakri Y, Sarrazin S, Mayer UP, Tillmanns S, Nerlov C, Boned A, Sieweke MH. Bakri Y, et al. Blood. 2005 Apr 1;105(7):2707-16. doi: 10.1182/blood-2004-04-1448. Epub 2004 Dec 14. Blood. 2005. PMID: 15598817 Free article.
Consistent with this, PU.1 directly bound to MafB, inhibited its transcriptional activity in macrophages, and repressed its ability to induce macrophage differentiation in chicken myeloid progenitors. We propose that high PU.1 activity favors DCs at the expen …
Consistent with this, PU.1 directly bound to MafB, inhibited its transcriptional activity in macrophages, and repressed its ab …
Small extracellular vesicles deliver osteolytic effectors and mediate cancer-induced osteolysis in bone metastatic niche.
Ma Q, Liang M, Wu Y, Dou C, Xu J, Dong S, Luo F. Ma Q, et al. J Extracell Vesicles. 2021 Feb;10(4):e12068. doi: 10.1002/jev2.12068. Epub 2021 Feb 18. J Extracell Vesicles. 2021. PMID: 33659051 Free PMC article.
Combined analysis of miRNAs profiles both in tumour-derived small EVs (sEVs) and osteoclasts identified miR-152-3p as a potential osteolytic molecule. sEVs were enriched in miR-152-3p, which targets osteoclastogenic regulator MAFB. Blocking miR-152-3p in sEVs upregulated t …
Combined analysis of miRNAs profiles both in tumour-derived small EVs (sEVs) and osteoclasts identified miR-152-3p as a potential osteolytic …
Role of MafB in macrophages.
Hamada M, Tsunakawa Y, Jeon H, Yadav MK, Takahashi S. Hamada M, et al. Exp Anim. 2020 Jan 29;69(1):1-10. doi: 10.1538/expanim.19-0076. Epub 2019 Oct 1. Exp Anim. 2020. PMID: 31582643 Free PMC article. Review.
The transcription factor MafB regulates macrophage differentiation. However, studies on the phenotype of Mafb-deficient macrophages are still limited. ...Studies using macrophage-specific Mafb-deficient mice show that MafB is linke …
The transcription factor MafB regulates macrophage differentiation. However, studies on the phenotype of Mafb-deficient …
Differential expression patterns of MafB and c-Maf in macrophages in vivo and in vitro.
Daassi D, Hamada M, Jeon H, Imamura Y, Nhu Tran MT, Takahashi S. Daassi D, et al. Biochem Biophys Res Commun. 2016 Apr 22;473(1):118-124. doi: 10.1016/j.bbrc.2016.03.063. Epub 2016 Mar 17. Biochem Biophys Res Commun. 2016. PMID: 26996125
The large Maf transcription factors c-Maf and MafB are expressed in macrophage-lineage hematopoietic cells, but the expression patterns of MafB and c-Maf in macrophage subtypes and tissue-resident macrophages have not been fully analyzed. ...In …
The large Maf transcription factors c-Maf and MafB are expressed in macrophage-lineage hematopoietic cells, but the expression …
126 results