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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1975 3
1976 1
1977 3
1978 1
1979 6
1980 8
1981 8
1982 12
1983 28
1984 25
1985 34
1986 54
1987 55
1988 38
1989 57
1990 81
1991 54
1992 70
1993 62
1994 110
1995 83
1996 72
1997 78
1998 76
1999 83
2000 87
2001 60
2002 72
2003 64
2004 80
2005 79
2006 82
2007 93
2008 90
2009 82
2010 90
2011 98
2012 126
2013 117
2014 100
2015 117
2016 140
2017 159
2018 143
2019 140
2020 172
2021 186
2022 192
2023 192
2024 147

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3,674 results

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Page 1
Revisiting the Role of Astrocytic MAOB in Parkinson's Disease.
Nam MH, Sa M, Ju YH, Park MG, Lee CJ. Nam MH, et al. Int J Mol Sci. 2022 Apr 18;23(8):4453. doi: 10.3390/ijms23084453. Int J Mol Sci. 2022. PMID: 35457272 Free PMC article. Review.
Monoamine oxidase-B (MAOB) has been believed to mediate the degradation of monoamine neurotransmitters such as dopamine. However, this traditional belief has been challenged by demonstrating that it is not MAOB but MAOA which mediates dopamine degradation. Instead, …
Monoamine oxidase-B (MAOB) has been believed to mediate the degradation of monoamine neurotransmitters such as dopamine. However, thi …
Stromal-derived MAOB promotes prostate cancer growth and progression.
Pu T, Wang J, Wei J, Zeng A, Zhang J, Chen J, Yin L, Li J, Lin TP, Melamed J, Corey E, Gao AC, Wu BJ. Pu T, et al. Sci Adv. 2024 Feb 9;10(6):eadi4935. doi: 10.1126/sciadv.adi4935. Epub 2024 Feb 9. Sci Adv. 2024. PMID: 38335292 Free PMC article.
Knockdown or overexpression of MAOB in human prostate stromal fibroblasts indicated that MAOB promotes cocultured PC cell proliferation, migration, and invasion and co-inoculated prostate tumor growth in mice. ...Pharmacological inhibition of stromal MAOB res …
Knockdown or overexpression of MAOB in human prostate stromal fibroblasts indicated that MAOB promotes cocultured PC cell prol …
Inhibition of MAOB Ameliorated High-Fat-Diet-Induced Atherosclerosis by Inhibiting Endothelial Dysfunction and Modulating Gut Microbiota.
Tian Z, Wang X, Han T, Wang M, Ning H, Sun C. Tian Z, et al. Nutrients. 2023 May 30;15(11):2542. doi: 10.3390/nu15112542. Nutrients. 2023. PMID: 37299505 Free PMC article.
MAOB small interfering RNA significantly attenuated the palmitic-acid (PA)-induced endothelial oxidative stress and dysfunction. ...The dual-luciferase reporter, Western blot and qPCR assay confirmed that miR-3620-5p directly regulated MAOB by binding to its mRNA 3' …
MAOB small interfering RNA significantly attenuated the palmitic-acid (PA)-induced endothelial oxidative stress and dysfunction. ...T …
Generation of Astrocyte-Specific MAOB Conditional Knockout Mouse with Minimal Tonic GABA Inhibition.
Lee JM, Sa M, An H, Kim JMJ, Kwon J, Yoon BE, Lee CJ. Lee JM, et al. Exp Neurobiol. 2022 Jun 30;31(3):158-172. doi: 10.5607/en22016. Exp Neurobiol. 2022. PMID: 35786639 Free PMC article.
Monoamine oxidase B (MAOB) is a key enzyme for GABA production in astrocytes in several brain regions. To date, the role of astrocytic MAOB has been studied in MAOB null knockout (KO) mice, although MAOB is expressed throughout the body. ...Using the C …
Monoamine oxidase B (MAOB) is a key enzyme for GABA production in astrocytes in several brain regions. To date, the role of astrocyti …
Association of the MAOB rs1799836 Single Nucleotide Polymorphism and APOE epsilon4 Allele in Alzheimer's Disease.
Babić Leko M, Nikolac Perković M, Nedić Erjavec G, Klepac N, Švob Štrac D, Borovečki F, Pivac N, Hof PR, Šimić G. Babić Leko M, et al. Curr Alzheimer Res. 2021;18(7):585-594. doi: 10.2174/1567205018666210917162843. Curr Alzheimer Res. 2021. PMID: 34533445
The MAOB rs1799836 polymorphism modulates MAOB transcription, consequently influencing protein translation and MAOB activity. We recently showed that cerebrospinal fluid levels of amyloid beta1-42 are decreased in patients carrying the A allele in MAOB …
The MAOB rs1799836 polymorphism modulates MAOB transcription, consequently influencing protein translation and MAOB act …
[MAOB: a modifier gene in phenylketonuria?].
Ghozlan A, Munnich A. Ghozlan A, et al. Med Sci (Paris). 2004 Oct;20(10):929-32. doi: 10.1051/medsci/20042010929. Med Sci (Paris). 2004. PMID: 15461973 Free article. Review. French.
We suggest here that monoamine oxidase type B, MAOB, an enzyme degrading phenylethylamine, a very toxic metabolite of phenylalanine, could act as a modifying gene since a variant enzymatic activity of MAOB in PKU patients with similar phenylalanine levels would resu …
We suggest here that monoamine oxidase type B, MAOB, an enzyme degrading phenylethylamine, a very toxic metabolite of phenylalanine, …
MP-Pt(IV): A MAOB-Sensitive Mitochondrial-Specific Prodrug for Treating Glioblastoma.
Raghavan S, Baskin DS, Sharpe MA. Raghavan S, et al. Mol Cancer Ther. 2020 Dec;19(12):2445-2453. doi: 10.1158/1535-7163.MCT-20-0420. Epub 2020 Oct 8. Mol Cancer Ther. 2020. PMID: 33033175
Coupling this MAOB-sensitive group to a nitrogen mustard produced a prodrug that damaged GBM mitochondria and killed GBM cells. ...Our studies demonstrate that MP-Pt(IV) is selectively activated by MAOB. MP-Pt(IV) is highly toxic toward GBM cells in vitro MP-Pt(IV) …
Coupling this MAOB-sensitive group to a nitrogen mustard produced a prodrug that damaged GBM mitochondria and killed GBM cells. ...Ou …
MAOB expression correlates with a favourable prognosis in prostate cancer, and its genetic variants are associated with the metastasis of the disease.
Huang HC, Hsieh YH, Hsiao CH, Lin CY, Wang SS, Ho KH, Chang LC, Huang HM, Yang SF, Chien MH. Huang HC, et al. J Cell Mol Med. 2024 Apr;28(8):e18229. doi: 10.1111/jcmm.18229. J Cell Mol Med. 2024. PMID: 38520217 Free PMC article.
Monoamine oxidase B (MAOB), a neurotransmitter-degrading enzyme, was reported to reveal conflicting roles in various cancers. ...Our findings suggest that MAOB may act as a suppressor of PCa progression, and the rs3027452 and rs1799836 genetic variants of MAOB …
Monoamine oxidase B (MAOB), a neurotransmitter-degrading enzyme, was reported to reveal conflicting roles in various cancers. ...Our …
(S)-5-Methoxymethyl-3-[6-(4,4,4-trifluorobutoxy)benzo[d]isoxazol-3-yl]-oxazolidin-2-[11C]one.
Leung K. Leung K. 2010 May 22 [updated 2010 Jul 7]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. 2010 May 22 [updated 2010 Jul 7]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. PMID: 20642018 Free Books & Documents. Review.
3,674 results