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Cluster-Analytic Identification of Clinically Meaningful Subtypes in MCAS: The Relevance of Heat and Cold.
Häder T, Molderings GJ, Klawonn F, Conrad R, Mücke M, Sellin J. Häder T, et al. Dig Dis Sci. 2023 Aug;68(8):3400-3412. doi: 10.1007/s10620-023-07921-5. Epub 2023 Apr 8. Dig Dis Sci. 2023. PMID: 37029308 Free PMC article.
The data used included data from a MCAS checklist asking about symptoms and triggers and a set of diagnostically relevant laboratory parameters. RESULTS: Using a two-step cluster analysis, MCAS patients could be divided into three clusters. Physical trigge …
The data used included data from a MCAS checklist asking about symptoms and triggers and a set of diagnostically relevant labo …
Mast cell activation syndrome: is anaphylaxis part of the phenotype? A systematic review.
Sabato V, Michel M, Blank U, Ebo DG, Vitte J. Sabato V, et al. Curr Opin Allergy Clin Immunol. 2021 Oct 1;21(5):426-434. doi: 10.1097/ACI.0000000000000768. Curr Opin Allergy Clin Immunol. 2021. PMID: 34292177
PURPOSE OF REVIEW: Mast cell activation syndrome (MCAS) and anaphylaxis are the result of a spontaneous or triggered pathological degranulation of mast cells (MCs) and might have as substrate normal or pathological MCs (increased burden, aberrant MCs or both). ...He …
PURPOSE OF REVIEW: Mast cell activation syndrome (MCAS) and anaphylaxis are the result of a spontaneous or triggered pathologi …
Pathogenic Mechanisms of Vaccine-Induced Immune Thrombotic Thrombocytopenia in People Receiving Anti-COVID-19 Adenoviral-Based Vaccines: A Proposal.
Azzarone B, Veneziani I, Moretta L, Maggi E. Azzarone B, et al. Front Immunol. 2021 Aug 13;12:728513. doi: 10.3389/fimmu.2021.728513. eCollection 2021. Front Immunol. 2021. PMID: 34484238 Free PMC article.
Vaccine-induced immune thrombotic thrombocytopenia (VITT) is characterized by high levels of serum IgG that bind PF4/polyanion complexes, thus triggering platelet activation. Therefore, identification of the fine pathophysiological mechanism by which vaccine components …
Vaccine-induced immune thrombotic thrombocytopenia (VITT) is characterized by high levels of serum IgG that bind PF4/polyanion complexes, th …
Suspected Mast Cell Activation Mimicking Heart Failure Exacerbation and Abdominal-Wall Cellulitis in a Resource-Limited Setting: A Case Report.
Tahajud OA, Elmi AH, Hussein AM. Tahajud OA, et al. Int Med Case Rep J. 2026 Apr 13;19:605332. doi: 10.2147/IMCRJ.S605332. eCollection 2026. Int Med Case Rep J. 2026. PMID: 42006547 Free PMC article.
Although cellulitis and heart failure exacerbation were initially considered, the combination of multisystem involvement, lack of infectious features, and recent trigger exposure supported a suspected mast-cell-mediated reaction, with MCAS considered in the differen …
Although cellulitis and heart failure exacerbation were initially considered, the combination of multisystem involvement, lack of infectious …