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Regulated IRE1α-dependent decay (RIDD)-mediated reprograming of lipid metabolism in cancer.
Almanza A, Mnich K, Blomme A, Robinson CM, Rodriguez-Blanco G, Kierszniowska S, McGrath EP, Le Gallo M, Pilalis E, Swinnen JV, Chatziioannou A, Chevet E, Gorman AM, Samali A. Almanza A, et al. Among authors: mcgrath ep. Nat Commun. 2022 May 6;13(1):2493. doi: 10.1038/s41467-022-30159-0. Nat Commun. 2022. PMID: 35524156 Free PMC article.
Death sentence: The tale of a fallen endoplasmic reticulum.
McGrath EP, Centonze FG, Chevet E, Avril T, Lafont E. McGrath EP, et al. Biochim Biophys Acta Mol Cell Res. 2021 May;1868(6):119001. doi: 10.1016/j.bbamcr.2021.119001. Epub 2021 Mar 9. Biochim Biophys Acta Mol Cell Res. 2021. PMID: 33705817 Free article. Review.
The Unfolded Protein Response in Breast Cancer.
McGrath EP, Logue SE, Mnich K, Deegan S, Jäger R, Gorman AM, Samali A. McGrath EP, et al. Cancers (Basel). 2018 Sep 21;10(10):344. doi: 10.3390/cancers10100344. Cancers (Basel). 2018. PMID: 30248920 Free PMC article. Review.
Inhibition of IRE1 RNase activity modulates the tumor cell secretome and enhances response to chemotherapy.
Logue SE, McGrath EP, Cleary P, Greene S, Mnich K, Almanza A, Chevet E, Dwyer RM, Oommen A, Legembre P, Godey F, Madden EC, Leuzzi B, Obacz J, Zeng Q, Patterson JB, Jäger R, Gorman AM, Samali A. Logue SE, et al. Among authors: mcgrath ep. Nat Commun. 2018 Aug 15;9(1):3267. doi: 10.1038/s41467-018-05763-8. Nat Commun. 2018. PMID: 30111846 Free PMC article.