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2017 5
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2019 9
2020 6
2021 6
2023 1
2024 0

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Page 1
Antimalarial activity of primaquine operates via a two-step biochemical relay.
Camarda G, Jirawatcharadech P, Priestley RS, Saif A, March S, Wong MHL, Leung S, Miller AB, Baker DA, Alano P, Paine MJI, Bhatia SN, O'Neill PM, Ward SA, Biagini GA. Camarda G, et al. Nat Commun. 2019 Jul 19;10(1):3226. doi: 10.1038/s41467-019-11239-0. Nat Commun. 2019. PMID: 31324806 Free PMC article.
Discovery of ABBV-4083, a novel analog of Tylosin A that has potent anti-Wolbachia and anti-filarial activity.
von Geldern TW, Morton HE, Clark RF, Brown BS, Johnston KL, Ford L, Specht S, Carr RA, Stolarik DF, Ma J, Rieser MJ, Struever D, Frohberger SJ, Koschel M, Ehrens A, Turner JD, Hübner MP, Hoerauf A, Taylor MJ, Ward SA, Marsh K, Kempf DJ. von Geldern TW, et al. PLoS Negl Trop Dis. 2019 Feb 28;13(2):e0007159. doi: 10.1371/journal.pntd.0007159. eCollection 2019 Feb. PLoS Negl Trop Dis. 2019. PMID: 30818326 Free PMC article.
AWZ1066S, a highly specific anti-Wolbachia drug candidate for a short-course treatment of filariasis.
Hong WD, Benayoud F, Nixon GL, Ford L, Johnston KL, Clare RH, Cassidy A, Cook DAN, Siu A, Shiotani M, Webborn PJH, Kavanagh S, Aljayyoussi G, Murphy E, Steven A, Archer J, Struever D, Frohberger SJ, Ehrens A, Hübner MP, Hoerauf A, Roberts AP, Hubbard ATM, Tate EW, Serwa RA, Leung SC, Qie L, Berry NG, Gusovsky F, Hemingway J, Turner JD, Taylor MJ, Ward SA, O'Neill PM. Hong WD, et al. Proc Natl Acad Sci U S A. 2019 Jan 22;116(4):1414-1419. doi: 10.1073/pnas.1816585116. Epub 2019 Jan 7. Proc Natl Acad Sci U S A. 2019. PMID: 30617067 Free PMC article.
Repurposing the orphan drug nitisinone to control the transmission of African trypanosomiasis.
Sterkel M, Haines LR, Casas-Sánchez A, Owino Adung'a V, Vionette-Amaral RJ, Quek S, Rose C, Silva Dos Santos M, García Escude N, Ismail HM, Paine MI, Barribeau SM, Wagstaff S, MacRae JI, Masiga D, Yakob L, Oliveira PL, Acosta-Serrano Á. Sterkel M, et al. PLoS Biol. 2021 Jan 26;19(1):e3000796. doi: 10.1371/journal.pbio.3000796. eCollection 2021 Jan. PLoS Biol. 2021. PMID: 33497373 Free PMC article.
33 results