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Ubiquitin modifications.

Swatek KN, Komander D. Swatek KN, et al. Cell Res. 2016 Apr;26(4):399-422. doi: 10.1038/cr.2016.39. Epub 2016 Mar 25. Cell Res. 2016. PMID: 27012465 Free PMC article. Review.

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The ubiquitin code.

Komander D, Rape M. Komander D, et al. Annu Rev Biochem. 2012;81:203-29. doi: 10.1146/annurev-biochem-060310-170328. Epub 2012 Apr 10. Annu Rev Biochem. 2012. PMID: 22524316 Review.

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Mechanisms of Deubiquitinase Specificity and Regulation.

Mevissen TET, Komander D. Mevissen TET, et al. Annu Rev Biochem. 2017 Jun 20;86:159-192. doi: 10.1146/annurev-biochem-061516-044916. Epub 2017 May 12. Annu Rev Biochem. 2017. PMID: 28498721 Review.

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The emerging complexity of protein ubiquitination.

Komander D. Komander D. Biochem Soc Trans. 2009 Oct;37(Pt 5):937-53. doi: 10.1042/BST0370937. Biochem Soc Trans. 2009. PMID: 19754430 Review.

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Breaking the chains: structure and function of the deubiquitinases.

Komander D, Clague MJ, Urbé S. Komander D, et al. Nat Rev Mol Cell Biol. 2009 Aug;10(8):550-63. doi: 10.1038/nrm2731. Nat Rev Mol Cell Biol. 2009. PMID: 19626045 Review.

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Molecular basis of USP7 inhibition by selective small-molecule inhibitors.

Turnbull AP, Ioannidis S, Krajewski WW, Pinto-Fernandez A, Heride C, Martin ACL, Tonkin LM, Townsend EC, Buker SM, Lancia DR, Caravella JA, Toms AV, Charlton TM, Lahdenranta J, Wilker E, Follows BC, Evans NJ, Stead L, Alli C, Zarayskiy VV, Talbot AC, Buckmelter AJ, Wang M, McKinnon CL, Saab F, McGouran JF, Century H, Gersch M, Pittman MS, Marshall CG, Raynham TM, Simcox M, Stewart LMD, McLoughlin SB, Escobedo JA, Bair KW, Dinsmore CJ, Hammonds TR, Kim S, Urbé S, Clague MJ, Kessler BM, Komander D. Turnbull AP, et al. Nature. 2017 Oct 26;550(7677):481-486. doi: 10.1038/nature24451. Epub 2017 Oct 18. Nature. 2017. PMID: 29045389 Free PMC article.

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Mechanism of parkin activation by PINK1.

Gladkova C, Maslen SL, Skehel JM, Komander D. Gladkova C, et al. Nature. 2018 Jul;559(7714):410-414. doi: 10.1038/s41586-018-0224-x. Epub 2018 Jun 6. Nature. 2018. PMID: 29995846 Free PMC article.

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The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity.

Damgaard RB, Walker JA, Marco-Casanova P, Morgan NV, Titheradge HL, Elliott PR, McHale D, Maher ER, McKenzie ANJ, Komander D. Damgaard RB, et al. Cell. 2016 Aug 25;166(5):1215-1230.e20. doi: 10.1016/j.cell.2016.07.019. Epub 2016 Aug 11. Cell. 2016. PMID: 27523608 Free PMC article.

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Ubiquitin Linkage-Specific Affimers Reveal Insights into K6-Linked Ubiquitin Signaling.

Michel MA, Swatek KN, Hospenthal MK, Komander D. Michel MA, et al. Mol Cell. 2017 Oct 5;68(1):233-246.e5. doi: 10.1016/j.molcel.2017.08.020. Epub 2017 Sep 21. Mol Cell. 2017. PMID: 28943312 Free PMC article.

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Mechanism of phospho-ubiquitin-induced PARKIN activation.

Wauer T, Simicek M, Schubert A, Komander D. Wauer T, et al. Nature. 2015 Aug 20;524(7565):370-4. doi: 10.1038/nature14879. Epub 2015 Jul 10. Nature. 2015. PMID: 26161729 Free PMC article.

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