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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2006 6
2007 3
2008 6
2009 5
2010 6
2011 8
2012 17
2013 9
2014 8
2015 5
2016 2
2017 4
2018 2
2020 0
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75 results
Results by year
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Page 1
Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPases.
Steger M, Tonelli F, Ito G, Davies P, Trost M, Vetter M, Wachter S, Lorentzen E, Duddy G, Wilson S, Baptista MA, Fiske BK, Fell MJ, Morrow JA, Reith AD, Alessi DR, Mann M. Steger M, et al. Elife. 2016 Jan 29;5:e12813. doi: 10.7554/eLife.12813. Elife. 2016. PMID: 26824392 Free PMC article.
Homo-PROTACs: bivalent small-molecule dimerizers of the VHL E3 ubiquitin ligase to induce self-degradation.
Maniaci C, Hughes SJ, Testa A, Chen W, Lamont DJ, Rocha S, Alessi DR, Romeo R, Ciulli A. Maniaci C, et al. Nat Commun. 2017 Oct 10;8(1):830. doi: 10.1038/s41467-017-00954-1. Nat Commun. 2017. PMID: 29018234 Free PMC article.
Structure of the LKB1-STRAD-MO25 complex reveals an allosteric mechanism of kinase activation.
Zeqiraj E, Filippi BM, Deak M, Alessi DR, van Aalten DM. Zeqiraj E, et al. Science. 2009 Dec 18;326(5960):1707-11. doi: 10.1126/science.1178377. Epub 2009 Nov 5. Science. 2009. PMID: 19892943 Free PMC article.
LKB1-dependent signaling pathways.
Alessi DR, Sakamoto K, Bayascas JR. Alessi DR, et al. Annu Rev Biochem. 2006;75:137-63. doi: 10.1146/annurev.biochem.75.103004.142702. Annu Rev Biochem. 2006. PMID: 16756488 Review.
The WNK-SPAK/OSR1 pathway: master regulator of cation-chloride cotransporters.
Alessi DR, Zhang J, Khanna A, Hochdörfer T, Shang Y, Kahle KT. Alessi DR, et al. Sci Signal. 2014 Jul 15;7(334):re3. doi: 10.1126/scisignal.2005365. Sci Signal. 2014. PMID: 25028718 Review.
LKB1 and AMPK and the cancer-metabolism link - ten years after.
Hardie DG, Alessi DR. Hardie DG, et al. BMC Biol. 2013 Apr 15;11:36. doi: 10.1186/1741-7007-11-36. BMC Biol. 2013. PMID: 23587167 Free PMC article. Review.
Structural Characterization of LRRK2 Inhibitors.
Gilsbach BK, Messias AC, Ito G, Sattler M, Alessi DR, Wittinghofer A, Kortholt A. Gilsbach BK, et al. J Med Chem. 2015 May 14;58(9):3751-6. doi: 10.1021/jm5018779. Epub 2015 May 1. J Med Chem. 2015. PMID: 25897865
Mechanism of activation of SGK3 by growth factors via the Class 1 and Class 3 PI3Ks.
Malik N, Macartney T, Hornberger A, Anderson KE, Tovell H, Prescott AR, Alessi DR. Malik N, et al. Biochem J. 2018 Jan 2;475(1):117-135. doi: 10.1042/BCJ20170650. Biochem J. 2018. PMID: 29150437 Free PMC article.
Disruption of the with no lysine kinase-STE20-proline alanine-rich kinase pathway reduces the hypertension induced by angiotensin II.
Cervantes-Perez LG, Castaneda-Bueno M, Jimenez JV, Vazquez N, Rojas-Vega L, Alessi DR, Bobadilla NA, Gamba G. Cervantes-Perez LG, et al. J Hypertens. 2018 Feb;36(2):361-367. doi: 10.1097/HJH.0000000000001554. J Hypertens. 2018. PMID: 28877076 Free PMC article.
Emerging roles of pseudokinases.
Boudeau J, Miranda-Saavedra D, Barton GJ, Alessi DR. Boudeau J, et al. Trends Cell Biol. 2006 Sep;16(9):443-52. doi: 10.1016/j.tcb.2006.07.003. Epub 2006 Aug 1. Trends Cell Biol. 2006. PMID: 16879967 Review.
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