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Page 1
The proteasome regulator PSME4 modulates proteasome activity and antigen diversity to abrogate antitumor immunity in NSCLC.
Javitt A, Shmueli MD, Kramer MP, Kolodziejczyk AA, Cohen IJ, Radomir L, Sheban D, Kamer I, Litchfield K, Bab-Dinitz E, Zadok O, Neiens V, Ulman A, Wolf-Levy H, Eisenberg-Lerner A, Kacen A, Alon M, Rêgo AT, Stacher-Priehse E, Lindner M, Koch I, Bar J, Swanton C, Samuels Y, Levin Y, da Fonseca PCA, Elinav E, Friedman N, Meiners S, Merbl Y. Javitt A, et al. Nat Cancer. 2023 May;4(5):629-647. doi: 10.1038/s43018-023-00557-4. Epub 2023 May 22. Nat Cancer. 2023. PMID: 37217651
Mitigating the risk of antimalarial resistance via covalent dual-subunit inhibition of the Plasmodium proteasome.
Deni I, Stokes BH, Ward KE, Fairhurst KJ, Pasaje CFA, Yeo T, Akbar S, Park H, Muir R, Bick DS, Zhan W, Zhang H, Liu YJ, Ng CL, Kirkman LA, Almaliti J, Gould AE, Duffey M, O'Donoghue AJ, Uhlemann AC, Niles JC, da Fonseca PCA, Gerwick WH, Lin G, Bogyo M, Fidock DA. Deni I, et al. Cell Chem Biol. 2023 May 18;30(5):470-485.e6. doi: 10.1016/j.chembiol.2023.03.002. Epub 2023 Mar 23. Cell Chem Biol. 2023. PMID: 36963402 Free PMC article.
Proteasome complexes experience profound structural and functional rearrangements throughout mammalian spermatogenesis.
Živković D, Sanchez Dafun A, Menneteau T, Schahl A, Lise S, Kervarrec C, Toste Rêgo A, da Fonseca PCA, Chavent M, Pineau C, Burlet-Schiltz O, Marcoux J, Bousquet MP. Živković D, et al. Proc Natl Acad Sci U S A. 2022 Apr 12;119(15):e2116826119. doi: 10.1073/pnas.2116826119. Epub 2022 Apr 4. Proc Natl Acad Sci U S A. 2022. PMID: 35377789 Free PMC article.
How to build a proteasome.
Morris EP, da Fonseca PCA. Morris EP, et al. Nat Struct Mol Biol. 2021 May;28(5):409-410. doi: 10.1038/s41594-021-00592-8. Nat Struct Mol Biol. 2021. PMID: 33927389 No abstract available.
Proceedings of the third CCP-EM Spring Symposium.
Burnley T, da Fonseca P. Burnley T, et al. Acta Crystallogr D Struct Biol. 2018 Jun 1;74(Pt 6):490-491. doi: 10.1107/S2059798318008239. Epub 2018 Jun 1. Acta Crystallogr D Struct Biol. 2018. PMID: 29872000 Free PMC article.