Metallopanstimulin-1 (MPS-1) mediates the promotion effect of leptin on colorectal cancer through activation of JNK/c-Jun signaling pathway.
Cao D, Luo Y, Qin S, Yu M, Mu Y, Ye G, Yang N, Cong Z, Chen J, Qin J, Cui R, Jing R, Cao H, Zhong M.
Cao D, et al.
Cell Death Dis. 2019 Sep 10;10(9):655. doi: 10.1038/s41419-019-1911-8.
Cell Death Dis. 2019.
PMID: 31506433
Free PMC article.
Leptin is implicated in obesity-associated CRC, but the underlying mechanism remains unclear. The current study identified over-expression of metallopanstimulin-1 (MPS-1) in CRC patients through microarray and histological analysis, especially in obese CRC patients. ...
Leptin is implicated in obesity-associated CRC, but the underlying mechanism remains unclear. The current study identified over-expression o …