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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1997 2
1998 3
1999 2
2000 4
2001 9
2002 10
2003 3
2004 6
2005 8
2006 8
2007 12
2008 6
2009 8
2010 9
2011 5
2012 8
2013 14
2014 13
2015 10
2016 4
2017 6
2018 7
2019 7
2020 11
2021 11
2022 5
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169 results
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Page 1
Epigenetic regulation in human melanoma: past and future.
Sarkar D, Leung EY, Baguley BC, Finlay GJ, Askarian-Amiri ME. Sarkar D, et al. Epigenetics. 2015;10(2):103-21. doi: 10.1080/15592294.2014.1003746. Epigenetics. 2015. PMID: 25587943 Free PMC article. Review.
Chronic mTOR activation induces a degradative smooth muscle cell phenotype.
Li G, Wang M, Caulk AW, Cilfone NA, Gujja S, Qin L, Chen PY, Chen Z, Yousef S, Jiao Y, He C, Jiang B, Korneva A, Bersi MR, Wang G, Liu X, Mehta S, Geirsson A, Gulcher JR, Chittenden TW, Simons M, Humphrey JD, Tellides G. Li G, et al. J Clin Invest. 2020 Mar 2;130(3):1233-1251. doi: 10.1172/JCI131048. J Clin Invest. 2020. PMID: 32039915 Free PMC article.
In addition to diminished contractile and synthetic functions, fate-mapped SMCs displayed increased proteolysis, endocytosis, phagocytosis, and lysosomal clearance of extracellular matrix and apoptotic cells. SMCs acquired a limited repertoire of macrophage markers and fun …
In addition to diminished contractile and synthetic functions, fate-mapped SMCs displayed increased proteolysis, endocytosis, phagocytosis, …
Uterine PEComas: A Morphologic, Immunohistochemical, and Molecular Analysis of 32 Tumors.
Bennett JA, Braga AC, Pinto A, Van de Vijver K, Cornejo K, Pesci A, Zhang L, Morales-Oyarvide V, Kiyokawa T, Zannoni GF, Carlson J, Slavik T, Tornos C, Antonescu CR, Oliva E. Bennett JA, et al. Am J Surg Pathol. 2018 Oct;42(10):1370-1383. doi: 10.1097/PAS.0000000000001119. Am J Surg Pathol. 2018. PMID: 30001237 Free PMC article.
All tumors were positive for HMB-45, cathepsin K, and at least one muscle marker, with most expressing melan-A (77%) and/or MiTF (79%). A PSF-TFE3 fusion was identified in one while another showed a RAD51B-OPHN1 fusion. ...
All tumors were positive for HMB-45, cathepsin K, and at least one muscle marker, with most expressing melan-A (77%) and/or MiTF (79% …
TGF-β Negatively Regulates Mitf-E Expression and Canine Osteoclastogenesis.
Asai K, Hisasue M, Shimokawa F, Funaba M, Murakami M. Asai K, et al. Biochem Genet. 2018 Oct;56(5):542-552. doi: 10.1007/s10528-018-9860-y. Epub 2018 Apr 21. Biochem Genet. 2018. PMID: 29680988
We previously reported in a murine cell system that gene induction of the E isoform of microphthalmia-associated transcription factor (Mitf-E) was required and sufficient for osteoclastogenesis, while transforming growth factor-beta (TGF-beta) enhanced RANKL-induced Mit …
We previously reported in a murine cell system that gene induction of the E isoform of microphthalmia-associated transcription factor (Mi …
Mitf and Tfe3: members of a b-HLH-ZIP transcription factor family essential for osteoclast development and function.
Hershey CL, Fisher DE. Hershey CL, et al. Bone. 2004 Apr;34(4):689-96. doi: 10.1016/j.bone.2003.08.014. Bone. 2004. PMID: 15050900 Review.
Mitf has been shown to reside downstream of the macrophage colony-stimulating factor (M-CSF) and receptor activator of NF-kappaB ligand (RANKL) signaling pathways that are critical for osteoclast proliferation, differentiation and function. ...Here, we review the bo …
Mitf has been shown to reside downstream of the macrophage colony-stimulating factor (M-CSF) and receptor activator of NF-kapp …
AP-1 and Mitf interact with NFATc1 to stimulate cathepsin K promoter activity in osteoclast precursors.
Pang M, Rodríguez-Gonzalez M, Hernandez M, Recinos CC, Seldeen KL, Troen BR. Pang M, et al. J Cell Biochem. 2019 Aug;120(8):12382-12392. doi: 10.1002/jcb.28504. Epub 2019 Feb 28. J Cell Biochem. 2019. PMID: 30816596
Our aim was to investigate the cooperative interplay among transcription factors AP-1, microphthalmia-associated transcription factor (Mitf), and NFATc1, and the consequent regulatory effects on CTSK transcription. Experiments were carried out in RAW 264.7 cells, which can …
Our aim was to investigate the cooperative interplay among transcription factors AP-1, microphthalmia-associated transcription factor (Mi …
Enhancement of RANKL-induced MITF-E expression and osteoclastogenesis by TGF-β.
Asai K, Funaba M, Murakami M. Asai K, et al. Cell Biochem Funct. 2014 Jul;32(5):401-9. doi: 10.1002/cbf.3028. Epub 2014 Feb 12. Cell Biochem Funct. 2014. PMID: 24519885
Microphthalmia-associated transcription factor (MITF) is a transcription factor that is expressed in limited types of cells, including osteoclasts, but the expression and role of MITF during osteoclastogenesis have not been fully elucidated. ...In particular, the re …
Microphthalmia-associated transcription factor (MITF) is a transcription factor that is expressed in limited types of cells, includin …
MITF and PU.1 recruit p38 MAPK and NFATc1 to target genes during osteoclast differentiation.
Sharma SM, Bronisz A, Hu R, Patel K, Mansky KC, Sif S, Ostrowski MC. Sharma SM, et al. J Biol Chem. 2007 May 25;282(21):15921-9. doi: 10.1074/jbc.M609723200. Epub 2007 Apr 2. J Biol Chem. 2007. PMID: 17403683 Free article.
Transcription factors NFATc1, PU.1, and MITF collaborate to regulate specific genes in response to colony-stimulating factor-1 (CSF-1) and receptor activator of NF-kappaB ligand (RANKL) signaling during osteoclast differentiation. ...In bone marrow-derived precursors, CSF- …
Transcription factors NFATc1, PU.1, and MITF collaborate to regulate specific genes in response to colony-stimulating factor-1 (CSF-1 …
Expression of histidine decarboxylase in melanocytes of the human skin.
Inami Y, Fukushima M, Murota H. Inami Y, et al. Biochem Biophys Res Commun. 2021 Jan 8;535:19-24. doi: 10.1016/j.bbrc.2020.12.033. Epub 2020 Dec 16. Biochem Biophys Res Commun. 2021. PMID: 33340761
., mast cells and basophils), which store histamine intracellularly, and inducible-type cells (e.g., keratinocytes and macrophages), which induce histidine decarboxylase (HDC, a key enzyme for histamine biosynthesis) activity but do not have a storage pool of histamine. .. …
., mast cells and basophils), which store histamine intracellularly, and inducible-type cells (e.g., keratinocytes and macrophages), …
Eos, MITF, and PU.1 recruit corepressors to osteoclast-specific genes in committed myeloid progenitors.
Hu R, Sharma SM, Bronisz A, Srinivasan R, Sankar U, Ostrowski MC. Hu R, et al. Mol Cell Biol. 2007 Jun;27(11):4018-27. doi: 10.1128/MCB.01839-06. Epub 2007 Apr 2. Mol Cell Biol. 2007. PMID: 17403896 Free PMC article.
We show that these factors can also repress transcription of target genes in committed myeloid precursors capable of forming either macrophages or osteoclasts. The direct interaction of MITF and PU.1 with the zinc finger protein Eos, an Ikaros family member, was nec …
We show that these factors can also repress transcription of target genes in committed myeloid precursors capable of forming either macro …
169 results