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Circulating levels of matrix gla protein and progression of aortic stenosis: a substudy of the Aortic Stenosis Progression Observation: Measuring Effects of rosuvastatin (ASTRONOMER) trial.

Capoulade R, Côté N, Mathieu P, Chan KL, Clavel MA, Dumesnil JG, Teo KK, Tam JW, Fournier D, Després JP, Pibarot P; ASTRONOMER Investigators. Capoulade R, et al. Can J Cardiol. 2014 Sep;30(9):1088-95. doi: 10.1016/j.cjca.2014.03.025. Epub 2014 Mar 24. Can J Cardiol. 2014. PMID: 25015689 Clinical Trial.

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Valvular disease in 2010: evolution and revolution in risk stratification and therapy.

Pibarot P. Pibarot P. Nat Rev Cardiol. 2011 Feb;8(2):75-7. doi: 10.1038/nrcardio.2010.204. Nat Rev Cardiol. 2011. PMID: 21270847 Review.

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NOTCH1 genetic variants in patients with tricuspid calcific aortic valve stenosis.

Ducharme V, Guauque-Olarte S, Gaudreault N, Pibarot P, Mathieu P, Bossé Y. Ducharme V, et al. J Heart Valve Dis. 2013 Mar;22(2):142-9. J Heart Valve Dis. 2013. PMID: 23798201 Free article.

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ATP acts as a survival signal and prevents the mineralization of aortic valve.

Côté N, El Husseini D, Pépin A, Guauque-Olarte S, Ducharme V, Bouchard-Cannon P, Audet A, Fournier D, Gaudreault N, Derbali H, McKee MD, Simard C, Després JP, Pibarot P, Bossé Y, Mathieu P. Côté N, et al. J Mol Cell Cardiol. 2012 May;52(5):1191-202. doi: 10.1016/j.yjmcc.2012.02.003. Epub 2012 Feb 16. J Mol Cell Cardiol. 2012. PMID: 22366713

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Replication of genetic association studies in aortic stenosis in adults.

Gaudreault N, Ducharme V, Lamontagne M, Guauque-Olarte S, Mathieu P, Pibarot P, Bossé Y. Gaudreault N, et al. Am J Cardiol. 2011 Nov 1;108(9):1305-10. doi: 10.1016/j.amjcard.2011.06.050. Epub 2011 Aug 18. Am J Cardiol. 2011. PMID: 21855833

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Hypoadiponectinemia is associated with valvular inflammation and faster disease progression in patients with aortic stenosis.

Mohty D, Pibarot P, Côté N, Cartier A, Audet A, Després JP, Mathieu P. Mohty D, et al. Cardiology. 2011;118(2):140-6. doi: 10.1159/000327588. Epub 2011 May 19. Cardiology. 2011. PMID: 21597293

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Angiotensin receptor blockers are associated with reduced fibrosis and interleukin-6 expression in calcific aortic valve disease.

Côté N, Mahmut A, Fournier D, Boulanger MC, Couture C, Després JP, Trahan S, Bossé Y, Pagé S, Pibarot P, Mathieu P. Côté N, et al. Pathobiology. 2014;81(1):15-24. doi: 10.1159/000350896. Epub 2013 Aug 21. Pathobiology. 2014. PMID: 23969418 Free article.

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Insulin resistance and LVH progression in patients with calcific aortic stenosis: a substudy of the ASTRONOMER trial.

Capoulade R, Clavel MA, Dumesnil JG, Chan KL, Teo KK, Tam JW, Côté N, Mathieu P, Després JP, Pibarot P; ASTRONOMER Investigators. Capoulade R, et al. JACC Cardiovasc Imaging. 2013 Feb;6(2):165-74. doi: 10.1016/j.jcmg.2012.11.004. JACC Cardiovasc Imaging. 2013. PMID: 23489530 Free article. Clinical Trial.

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Metabolic syndrome is associated with more pronounced impairment of left ventricle geometry and function in patients with calcific aortic stenosis: a substudy of the ASTRONOMER (Aortic Stenosis Progression Observation Measuring Effects of Rosuvastatin).

Pagé A, Dumesnil JG, Clavel MA, Chan KL, Teo KK, Tam JW, Mathieu P, Després JP, Pibarot P; ASTRONOMER Investigators. Pagé A, et al. J Am Coll Cardiol. 2010 Apr 27;55(17):1867-74. doi: 10.1016/j.jacc.2009.11.083. J Am Coll Cardiol. 2010. PMID: 20413039 Free article. Clinical Trial.

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Cardiovascular magnetic resonance evaluation of aortic stenosis severity using single plane measurement of effective orifice area.

Garcia J, Marrufo OR, Rodriguez AO, Larose E, Pibarot P, Kadem L. Garcia J, et al. J Cardiovasc Magn Reson. 2012 Apr 6;14(1):23. doi: 10.1186/1532-429X-14-23. J Cardiovasc Magn Reson. 2012. PMID: 22480269 Free PMC article.

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