MR/N002679/1/MRC_/Medical Research Council/United Kingdom[Grant Number] - Search Results

Year	Number of Results
2015	2
2016	5
2017	14
2018	18
2019	19
2020	10
2021	16
2022	7
2023	3
2024	0

1

High-throughput screen with the l,d-transpeptidase Ldt_Mt2 of Mycobacterium tuberculosis reveals novel classes of covalently reacting inhibitors.

de Munnik M, Lang PA, De Dios Anton F, Cacho M, Bates RH, Brem J, Rodríguez Miquel B, Schofield CJ. de Munnik M, et al. Chem Sci. 2023 May 30;14(26):7262-7278. doi: 10.1039/d2sc06858c. eCollection 2023 Jul 5. Chem Sci. 2023. PMID: 37416715 Free PMC article.

2

Tautomer-Specific Deacylation and Ω-Loop Flexibility Explain the Carbapenem-Hydrolyzing Broad-Spectrum Activity of the KPC-2 β-Lactamase.

Tooke CL, Hinchliffe P, Beer M, Zinovjev K, Colenso CK, Schofield CJ, Mulholland AJ, Spencer J. Tooke CL, et al. J Am Chem Soc. 2023 Apr 5;145(13):7166-7180. doi: 10.1021/jacs.2c12123. Epub 2023 Mar 27. J Am Chem Soc. 2023. PMID: 36972204 Free PMC article.

3

A conserved zinc-binding site in Acinetobacter baumannii PBP2 required for elongasome-directed bacterial cell shape.

Micelli C, Dai Y, Raustad N, Isberg RR, Dowson CG, Lloyd AJ, Geisinger E, Crow A, Roper DI. Micelli C, et al. Proc Natl Acad Sci U S A. 2023 Feb 21;120(8):e2215237120. doi: 10.1073/pnas.2215237120. Epub 2023 Feb 14. Proc Natl Acad Sci U S A. 2023. PMID: 36787358 Free PMC article.

4

Coupling Novel Probes with Molecular Localization Microscopy Reveals Cell Wall Homeostatic Mechanisms in Staphylococcus aureus.

Lund VA, Gangotra H, Zhao Z, Sutton JAF, Wacnik K, DeMeester K, Liang H, Santiago C, Leimkuhler Grimes C, Jones S, Foster SJ. Lund VA, et al. ACS Chem Biol. 2022 Dec 16;17(12):3298-3305. doi: 10.1021/acschembio.2c00741. Epub 2022 Nov 22. ACS Chem Biol. 2022. PMID: 36414253 Free PMC article.

5

Peptidoglycan maturation controls outer membrane protein assembly.

Mamou G, Corona F, Cohen-Khait R, Housden NG, Yeung V, Sun D, Sridhar P, Pazos M, Knowles TJ, Kleanthous C, Vollmer W. Mamou G, et al. Nature. 2022 Jun;606(7916):953-959. doi: 10.1038/s41586-022-04834-7. Epub 2022 Jun 15. Nature. 2022. PMID: 35705811 Free PMC article.

6

Penicillin-Binding Protein 1 (PBP1) of Staphylococcus aureus Has Multiple Essential Functions in Cell Division.

Wacnik K, Rao VA, Chen X, Lafage L, Pazos M, Booth S, Vollmer W, Hobbs JK, Lewis RJ, Foster SJ. Wacnik K, et al. mBio. 2022 Aug 30;13(4):e0066922. doi: 10.1128/mbio.00669-22. Epub 2022 Jun 15. mBio. 2022. PMID: 35703435 Free PMC article.

7

Penicillin Derivatives Inhibit the SARS-CoV-2 Main Protease by Reaction with Its Nucleophilic Cysteine.

Malla TR, Brewitz L, Muntean DG, Aslam H, Owen CD, Salah E, Tumber A, Lukacik P, Strain-Damerell C, Mikolajek H, Walsh MA, Schofield CJ. Malla TR, et al. J Med Chem. 2022 Jun 9;65(11):7682-7696. doi: 10.1021/acs.jmedchem.1c02214. Epub 2022 May 12. J Med Chem. 2022. PMID: 35549342 Free PMC article.

8

Plant peptidoglycan precursor biosynthesis: Conservation between moss chloroplasts and Gram-negative bacteria.

Dowson AJ, Lloyd AJ, Cuming AC, Roper DI, Frigerio L, Dowson CG. Dowson AJ, et al. Plant Physiol. 2022 Aug 29;190(1):165-179. doi: 10.1093/plphys/kiac176. Plant Physiol. 2022. PMID: 35471580 Free PMC article.

9

Structural basis of lipopolysaccharide maturation by the O-antigen ligase.

Ashraf KU, Nygaard R, Vickery ON, Erramilli SK, Herrera CM, McConville TH, Petrou VI, Giacometti SI, Dufrisne MB, Nosol K, Zinkle AP, Graham CLB, Loukeris M, Kloss B, Skorupinska-Tudek K, Swiezewska E, Roper DI, Clarke OB, Uhlemann AC, Kossiakoff AA, Trent MS, Stansfeld PJ, Mancia F. Ashraf KU, et al. Nature. 2022 Apr;604(7905):371-376. doi: 10.1038/s41586-022-04555-x. Epub 2022 Apr 6. Nature. 2022. PMID: 35388216 Free PMC article.

10

Studies on the Reactions of Biapenem with VIM Metallo β-Lactamases and the Serine β-Lactamase KPC-2.

Lucic A, Malla TR, Calvopiña K, Tooke CL, Brem J, McDonough MA, Spencer J, Schofield CJ. Lucic A, et al. Antibiotics (Basel). 2022 Mar 16;11(3):396. doi: 10.3390/antibiotics11030396. Antibiotics (Basel). 2022. PMID: 35326858 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Results by year

Text availability

Article attribute

Article type

Publication date

88 results

Results by year

Search Page

Filters

My NCBI Filters

Results by year

Text availability

Article attribute

Article type

Publication date

Search Results

88 results

Results by year