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Page 1
Ischemia-Selective Cardioprotection by Malonate for Ischemia/Reperfusion Injury.
Prag HA, Aksentijevic D, Dannhorn A, Giles AV, Mulvey JF, Sauchanka O, Du L, Bates G, Reinhold J, Kula-Alwar D, Xu Z, Pellerin L, Goodwin RJA, Murphy MP, Krieg T. Prag HA, et al. Circ Res. 2022 Sep 2;131(6):528-541. doi: 10.1161/CIRCRESAHA.121.320717. Epub 2022 Aug 12. Circ Res. 2022. PMID: 35959683 Free PMC article.
Mitochondria as Therapeutic Targets in Transplantation.
Saeb-Parsy K, Martin JL, Summers DM, Watson CJE, Krieg T, Murphy MP. Saeb-Parsy K, et al. Trends Mol Med. 2021 Feb;27(2):185-198. doi: 10.1016/j.molmed.2020.08.001. Epub 2020 Sep 17. Trends Mol Med. 2021. PMID: 32952044 Free article. Review.
Targeting Succinate Metabolism in Ischemia/Reperfusion Injury.
Kula-Alwar D, Prag HA, Krieg T. Kula-Alwar D, et al. Circulation. 2019 Dec 10;140(24):1968-1970. doi: 10.1161/CIRCULATIONAHA.119.042791. Epub 2019 Dec 9. Circulation. 2019. PMID: 31815541 Review. No abstract available.
Mechanism of succinate efflux upon reperfusion of the ischaemic heart.
Prag HA, Gruszczyk AV, Huang MM, Beach TE, Young T, Tronci L, Nikitopoulou E, Mulvey JF, Ascione R, Hadjihambi A, Shattock MJ, Pellerin L, Saeb-Parsy K, Frezza C, James AM, Krieg T, Murphy MP, Aksentijević D. Prag HA, et al. Cardiovasc Res. 2021 Mar 21;117(4):1188-1201. doi: 10.1093/cvr/cvaa148. Cardiovasc Res. 2021. PMID: 32766828 Free PMC article.
Selective mitochondrial superoxide generation in vivo is cardioprotective through hormesis.
Antonucci S, Mulvey JF, Burger N, Di Sante M, Hall AR, Hinchy EC, Caldwell ST, Gruszczyk AV, Deshwal S, Hartley RC, Kaludercic N, Murphy MP, Di Lisa F, Krieg T. Antonucci S, et al. Free Radic Biol Med. 2019 Apr;134:678-687. doi: 10.1016/j.freeradbiomed.2019.01.034. Epub 2019 Feb 4. Free Radic Biol Med. 2019. PMID: 30731114 Free PMC article.
ND3 Cys39 in complex I is exposed during mitochondrial respiration.
Burger N, James AM, Mulvey JF, Hoogewijs K, Ding S, Fearnley IM, Loureiro-López M, Norman AAI, Arndt S, Mottahedin A, Sauchanka O, Hartley RC, Krieg T, Murphy MP. Burger N, et al. Cell Chem Biol. 2022 Apr 21;29(4):636-649.e14. doi: 10.1016/j.chembiol.2021.10.010. Epub 2021 Nov 4. Cell Chem Biol. 2022. PMID: 34739852 Free PMC article.