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[Effect of tunicamycin combined with cisplatin on proliferation and apoptosis of human nasopharyngeal carcinoma cells in vitro].
Song L, Ma L, Zhang X, Jiang Z, Liu H, Jiang C. Song L, et al. Nan Fang Yi Ke Da Xue Xue Bao. 2012 Jun;32(6):766-71. Nan Fang Yi Ke Da Xue Xue Bao. 2012. PMID: 22699051 Chinese.
The expressions of Bax, Bcl-2, and GRP78 in cells treated with 3 µmol/L tunicamycin with or without 6.00 µmol/L cisplatin were measured with Western blotting. ...Tunicamycin at 0.3 µmol/L combined with 0.6 µmol/L cisplatin showed an obviously enhanced …
The expressions of Bax, Bcl-2, and GRP78 in cells treated with 3 µmol/L tunicamycin with or without 6.00 µmol/L cisplatin were …
[2-deoxyglucose inhibits angiogenesis of rheumatoid arthritis via activating AMPK pathway].
Wang Y, Wei Y, Cheng X, Sun X, Ma L, Song Y, Zhou J, Wei F, Liu H. Wang Y, et al. Nan Fang Yi Ke Da Xue Xue Bao. 2018 Jul 30;38(8):962-968. doi: 10.3969/j.issn.1673-4254.2018.08.10. Nan Fang Yi Ke Da Xue Xue Bao. 2018. PMID: 30187877 Free PMC article. Chinese.

RESULTS: 2-DG (200 mg/kg) obviously decreased appearance of synovial pannus (P < 0.01); in vitro, 2-DG (0.5 mmol/L and/or 5 mmol/L) obviously inhibited proliferation, migration and tube number of HUVEC (P < 0.01 or P < 0.001), and its effects on HUVEC were

RESULTS: 2-DG (200 mg/kg) obviously decreased appearance of synovial pannus (P < 0.01); in vitro, 2-DG (0.5 mmol/L and/or 5 mmol/

Synergistic antitumor effect of 3-bromopyruvate and 5-fluorouracil against human colorectal cancer through cell cycle arrest and induction of apoptosis.
Chong D, Ma L, Liu F, Zhang Z, Zhao S, Huo Q, Zhang P, Zheng H, Liu H. Chong D, et al. Anticancer Drugs. 2017 Sep;28(8):831-840. doi: 10.1097/CAD.0000000000000517. Anticancer Drugs. 2017. PMID: 28816773
Non-benzoquinone geldanamycin analogs trigger various forms of death in human breast cancer cells.
Zhang Z, Li HM, Zhou C, Li Q, Ma L, Zhang Z, Sun Y, Wang L, Zhang X, Zhu B, Hong YS, Wu CZ, Liu H. Zhang Z, et al. J Exp Clin Cancer Res. 2016 Sep 22;35(1):149. doi: 10.1186/s13046-016-0428-6. J Exp Clin Cancer Res. 2016. PMID: 27658586 Free PMC article.
[Effects of LCL161, a Smac mimetic on the proliferation and apoptosis in hepatocellular carcinoma cells].
Ren K, Ma L, Chong D, Zhang Z, Zhou C, Liu H, Zhao S. Ren K, et al. Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2016 Sep 28;41(9):898-904. doi: 10.11817/j.issn.1672-7347.2016.09.003. Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2016. PMID: 27640787 Chinese.
RESULTS: LCL161 displayed notable antiproliferative activity on HCC cells at the concentrations of 1-16 μmol/L (P<0.01), with IC50 values of 4.3 and 4.9 μmol/L for HepG2 and SMMC7721 cells, respectively, after treatment for 48 h. ...LCL161 induced significant ap …
RESULTS: LCL161 displayed notable antiproliferative activity on HCC cells at the concentrations of 1-16 μmol/L (P<0.01), with IC5 …
[Autophagy inhibitor 3-methyladenine enhances the sensitivity of nasopharyngeal carcinoma cells to chemotherapy and radiotherapy].
Song L, Ma L, Chen G, Huang Y, Sun X, Jiang C, Liu H. Song L, et al. Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2016 Jan;41(1):9-18. doi: 10.11817/j.issn.1672-7347.2016.01.002. Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2016. PMID: 26819419 Chinese.
OBJECTIVE: To explore the effects of 3-methyladenine (3-MA, an autophagy inhibitor) on sensitivities of nasopharyngeal carcinoma cells to radiotherapy and chemotherapy and the underlying mechanisms.
...Compared with control group, pretreatment with 1 mmol/L of 3- …
OBJECTIVE: To explore the effects of 3-methyladenine (3-MA, an autophagy inhibitor) on sensitivities of nasopharyngeal carcinoma cell …
Inhibition of autophagy by 3-MA enhances endoplasmic reticulum stress-induced apoptosis in human nasopharyngeal carcinoma cells.
Song L, Liu H, Ma L, Zhang X, Jiang Z, Jiang C. Song L, et al. Oncol Lett. 2013 Oct;6(4):1031-1038. doi: 10.3892/ol.2013.1498. Epub 2013 Jul 29. Oncol Lett. 2013. PMID: 24137459 Free PMC article.
Combining 3-methyladenine (3-MA) with cisplatin (DDP), ionizing radiation (IR), 2-deoxy-D-glucose (2-DG) or tunicamycin (TM) resulted in enhanced cell death, as revealed by MTT and colony formation assays. ...Using fluorescence microscopy, 3-MA was identified to inc …
Combining 3-methyladenine (3-MA) with cisplatin (DDP), ionizing radiation (IR), 2-deoxy-D-glucose (2-DG) or tunicamycin (TM) resulted …
[Chloroquine induces apoptosis of human hepatocellular carcinoma cells in vitro by miR-26b-mediated regulation of Mcl-1].
Sun XJ, Ma LY, Zhang MX, Wang Y, Zhang P, Jiang CC, Liu H. Sun XJ, et al. Nan Fang Yi Ke Da Xue Xue Bao. 2018 Apr 20;38(4):409-413. doi: 10.3969/j.issn.1673-4254.2018.04.07. Nan Fang Yi Ke Da Xue Xue Bao. 2018. PMID: 29735440 Free PMC article. Chinese.
Treatments with 80 µmol/L chloroquine for 24, 48, and 72 h induced survival rates of (71.59∓0.2)%, (45.40∓0.5)%, and (26.34∓1.4)% in the cells. Treatments with chloroquine at 40, 80, and 160 µmol/L for 5 h resulted in obviously lowered intracellular ATP levels in th …
Treatments with 80 µmol/L chloroquine for 24, 48, and 72 h induced survival rates of (71.59∓0.2)%, (45.40∓0.5)%, and (26.34∓1.4)% in …
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