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Heteroplasmy levels of a mitochondrial gene mutation associated with diabetes mellitus decrease in leucocyte DNA upon aging.
't Hart LM, Jansen JJ, Lemkes HH, de Knijff P, Maassen JA. 't Hart LM, et al. Among authors: maassen ja. Hum Mutat. 1996;7(3):193-7. doi: 10.1002/(SICI)1098-1004(1996)7:3<193::AID-HUMU2>3.0.CO;2-C. Hum Mutat. 1996. PMID: 8829651
The association of mitochondrial content with prevalent and incident type 2 diabetes.
Reiling E, Ling C, Uitterlinden AG, Van't Riet E, Welschen LM, Ladenvall C, Almgren P, Lyssenko V, Nijpels G, van Hove EC, Maassen JA, de Geus EJ, Boomsma DI, Dekker JM, Groop L, Willemsen G, 't Hart LM. Reiling E, et al. Among authors: maassen ja. J Clin Endocrinol Metab. 2010 Apr;95(4):1909-15. doi: 10.1210/jc.2009-1775. Epub 2010 Feb 11. J Clin Endocrinol Metab. 2010. PMID: 20150578
Genetic association analysis of 13 nuclear-encoded mitochondrial candidate genes with type II diabetes mellitus: the DAMAGE study.
Reiling E, van Vliet-Ostaptchouk JV, van 't Riet E, van Haeften TW, Arp PA, Hansen T, Kremer D, Groenewoud MJ, van Hove EC, Romijn JA, Smit JW, Nijpels G, Heine RJ, Uitterlinden AG, Pedersen O, Slagboom PE, Maassen JA, Hofker MH, 't Hart LM, Dekker JM. Reiling E, et al. Among authors: maassen ja. Eur J Hum Genet. 2009 Aug;17(8):1056-62. doi: 10.1038/ejhg.2009.4. Epub 2009 Feb 11. Eur J Hum Genet. 2009. PMID: 19209188 Free PMC article.
Lessons that can be learned from patients with diabetogenic mutations in mitochondrial DNA: implications for common type 2 diabetes.
Maassen JA, 't Hart LM, Ouwens DM. Maassen JA, et al. Curr Opin Clin Nutr Metab Care. 2007 Nov;10(6):693-7. doi: 10.1097/MCO.0b013e3282f0b774. Curr Opin Clin Nutr Metab Care. 2007. PMID: 18089949 Review.
Molecular mechanisms of mitochondrial diabetes (MIDD).
Maassen JA, Janssen GM, 't Hart LM. Maassen JA, et al. Ann Med. 2005;37(3):213-21. doi: 10.1080/07853890510007188. Ann Med. 2005. PMID: 16019720 Review.
New insights in the molecular pathogenesis of the maternally inherited diabetes and deafness syndrome.
Maassen JA, Jahangir Tafrechi RS, Janssen GM, Raap AK, Lemkes HH, 't Hart LM. Maassen JA, et al. Endocrinol Metab Clin North Am. 2006 Jun;35(2):385-96, x-xi. doi: 10.1016/j.ecl.2006.02.014. Endocrinol Metab Clin North Am. 2006. PMID: 16632100 Review.
Simultaneous A8344G heteroplasmy and mitochondrial DNA copy number quantification in myoclonus epilepsy and ragged-red fibers (MERRF) syndrome by a multiplex molecular beacon based real-time fluorescence PCR.
Szuhai K, Ouweland J, Dirks R, Lemaître M, Truffert J, Janssen G, Tanke H, Holme E, Maassen J, Raap A. Szuhai K, et al. Among authors: maassen j. Nucleic Acids Res. 2001 Feb 1;29(3):E13. doi: 10.1093/nar/29.3.e13. Nucleic Acids Res. 2001. PMID: 11160915 Free PMC article.
Elongation factor-1 messenger-RNA levels in cultured cells are high compared to tissue and are not drastically affected further by oncogenic transformation.
Sanders J, Maassen JA, Möller W. Sanders J, et al. Among authors: maassen ja. Nucleic Acids Res. 1992 Nov 25;20(22):5907-10. doi: 10.1093/nar/20.22.5907. Nucleic Acids Res. 1992. PMID: 1461723 Free PMC article.
An insulin receptor mutant (Asp707 --> Ala), involved in leprechaunism, is processed and transported to the cell surface but unable to bind insulin.
Hart LM, Lindhout D, Van der Zon GC, Kayserilli H, Apak MY, Kleijer WJ, Van der Vorm ER, Maassen JA. Hart LM, et al. Among authors: maassen ja. J Biol Chem. 1996 Aug 2;271(31):18719-24. doi: 10.1074/jbc.271.31.18719. J Biol Chem. 1996. PMID: 8702527
Tissue-related changes in insulin receptor number and autophosphorylation induced by starvation and diabetes in rats.
Koopmans SJ, Maassen JA, Sips HC, Radder JK, Krans HM. Koopmans SJ, et al. Among authors: maassen ja. Metabolism. 1995 Mar;44(3):291-7. doi: 10.1016/0026-0495(95)90157-4. Metabolism. 1995. PMID: 7885272
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