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Probing enzyme quaternary structure by combinatorial mutagenesis and selection.
MacBeath G, Kast P, Hilvert D. MacBeath G, et al. Protein Sci. 1998 Aug;7(8):1757-67. doi: 10.1002/pro.5560070810. Protein Sci. 1998. PMID: 10082372 Free PMC article.
Redesigning enzyme topology by directed evolution.
MacBeath G, Kast P, Hilvert D. MacBeath G, et al. Science. 1998 Mar 20;279(5358):1958-61. doi: 10.1126/science.279.5358.1958. Science. 1998. PMID: 9506949
Hydrolytic antibodies: variations on a theme.
MacBeath G, Hilvert D. MacBeath G, et al. Chem Biol. 1996 Jun;3(6):433-45. doi: 10.1016/s1074-5521(96)90091-5. Chem Biol. 1996. PMID: 8807874 Review.
PDZ domain binding selectivity is optimized across the mouse proteome.
Stiffler MA, Chen JR, Grantcharova VP, Lei Y, Fuchs D, Allen JE, Zaslavskaia LA, MacBeath G. Stiffler MA, et al. Science. 2007 Jul 20;317(5836):364-9. doi: 10.1126/science.1144592. Science. 2007. PMID: 17641200 Free PMC article.
Predicting PDZ domain-peptide interactions from primary sequences.
Chen JR, Chang BH, Allen JE, Stiffler MA, MacBeath G. Chen JR, et al. Nat Biotechnol. 2008 Sep;26(9):1041-5. doi: 10.1038/nbt.1489. Nat Biotechnol. 2008. PMID: 18711339 Free PMC article.
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