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Huntington's disease: the case for genetic modifiers.
Gusella JF, MacDonald ME. Gusella JF, et al. Genome Med. 2009 Aug 21;1(8):80. doi: 10.1186/gm80. Genome Med. 2009. PMID: 19725930 Free PMC article.
The Huntington's disease candidate region exhibits many different haplotypes.
MacDonald ME, Novelletto A, Lin C, Tagle D, Barnes G, Bates G, Taylor S, Allitto B, Altherr M, Myers R, et al. MacDonald ME, et al. Nat Genet. 1992 May;1(2):99-103. doi: 10.1038/ng0592-99. Nat Genet. 1992. PMID: 1302016 Review.
Assay by polymerase chain reaction (PCR) of multi-allele polymorphisms in the Huntington's disease region of chromosome 4.
Allitto BA, McClatchey AI, Barnes G, Altherr M, Wasmuth J, Frischauf AM, MacDonald ME, Gusella J. Allitto BA, et al. Mol Cell Probes. 1992 Dec;6(6):513-20. doi: 10.1016/0890-8508(92)90048-3. Mol Cell Probes. 1992. PMID: 1480191
Increased recombination adjacent to the Huntington disease-linked D4S10 marker.
Allitto BA, MacDonald ME, Bucan M, Richards J, Romano D, Whaley WL, Falcone B, Ianazzi J, Wexler NS, Wasmuth JJ, et al. Allitto BA, et al. Genomics. 1991 Jan;9(1):104-12. doi: 10.1016/0888-7543(91)90226-5. Genomics. 1991. PMID: 1672283
Complex patterns of linkage disequilibrium in the Huntington disease region.
MacDonald ME, Lin C, Srinidhi L, Bates G, Altherr M, Whaley WL, Lehrach H, Wasmuth J, Gusella JF. MacDonald ME, et al. Am J Hum Genet. 1991 Oct;49(4):723-34. Am J Hum Genet. 1991. PMID: 1680285 Free PMC article.
New DNA markers in the Huntington's disease gene candidate region.
Lin CS, Altherr M, Bates G, Whaley WL, Read AP, Harris R, Lehrach H, Wasmuth JJ, Gusella JF, MacDonald ME. Lin CS, et al. Somat Cell Mol Genet. 1991 Sep;17(5):481-8. doi: 10.1007/BF01233172. Somat Cell Mol Genet. 1991. PMID: 1684879
Huntington disease-linked locus D4S111 exposed as the alpha-L-iduronidase gene.
MacDonald ME, Scott HS, Whaley WL, Pohl T, Wasmuth JJ, Lehrach H, Morris CP, Frischauf AM, Hopwood JJ, Gusella JF. MacDonald ME, et al. Somat Cell Mol Genet. 1991 Jul;17(4):421-5. doi: 10.1007/BF01233067. Somat Cell Mol Genet. 1991. PMID: 1832239
Synteny on mouse chromosome 5 of homologs for human DNA loci linked to the Huntington disease gene.
Cheng SV, Martin GR, Nadeau JH, Haines JL, Bucan M, Kozak CA, MacDonald ME, Lockyer JL, Ledley FD, Woo SL, et al. Cheng SV, et al. Genomics. 1989 Apr;4(3):419-26. doi: 10.1016/0888-7543(89)90349-2. Genomics. 1989. PMID: 2523855
Clustering of multiallele DNA markers near the Huntington's disease gene.
MacDonald ME, Cheng SV, Zimmer M, Haines JL, Poustka A, Allitto B, Smith B, Whaley WL, Romano DM, Jagadeesh J, et al. MacDonald ME, et al. J Clin Invest. 1989 Sep;84(3):1013-6. doi: 10.1172/JCI114222. J Clin Invest. 1989. PMID: 2569477 Free PMC article.
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