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Page 1
Lineage-specific events underlie aortic root aneurysm pathogenesis in Loeys-Dietz syndrome.
MacFarlane EG, Parker SJ, Shin JY, Kang BE, Ziegler SG, Creamer TJ, Bagirzadeh R, Bedja D, Chen Y, Calderon JF, Weissler K, Frischmeyer-Guerrerio PA, Lindsay ME, Habashi JP, Dietz HC. MacFarlane EG, et al. J Clin Invest. 2019 Feb 1;129(2):659-675. doi: 10.1172/JCI123547. Epub 2019 Jan 7. J Clin Invest. 2019. PMID: 30614814 Free PMC article.
Epigenetic activation and memory at a TGFB2 enhancer in systemic sclerosis.
Shin JY, Beckett JD, Bagirzadeh R, Creamer TJ, Shah AA, McMahan Z, Paik JJ, Sampedro MM, MacFarlane EG, Beer MA, Warren D, Wigley FM, Dietz HC. Shin JY, et al. Among authors: macfarlane eg. Sci Transl Med. 2019 Jun 19;11(497):eaaw0790. doi: 10.1126/scitranslmed.aaw0790. Sci Transl Med. 2019. PMID: 31217334 Free PMC article.
Calpain 9 as a therapeutic target in TGFβ-induced mesenchymal transition and fibrosis.
Kim DH, Beckett JD, Nagpal V, Seman-Senderos MA, Gould RA, Creamer TJ, MacFarlane EG, Chen Y, Bedja D, Butcher JT, Mitzner W, Rouf R, Hata S, Warren DS, Dietz HC. Kim DH, et al. Among authors: macfarlane eg. Sci Transl Med. 2019 Jul 17;11(501):eaau2814. doi: 10.1126/scitranslmed.aau2814. Sci Transl Med. 2019. PMID: 31316008 Free PMC article.
Early clinical outcomes and molecular smooth muscle cell phenotyping using a prophylactic aortic arch replacement strategy in Loeys-Dietz syndrome.
Pedroza AJ, Cheng P, Dalal AR, Baeumler K, Kino A, Tognozzi E, Shad R, Yokoyama N, Nakamura K, Mitchel O, Hiesinger W, MacFarlane EG, Fleischmann D, Woo YJ, Quertermous T, Fischbein MP. Pedroza AJ, et al. Among authors: macfarlane eg. J Thorac Cardiovasc Surg. 2023 Nov;166(5):e332-e376. doi: 10.1016/j.jtcvs.2023.07.023. Epub 2023 Jul 25. J Thorac Cardiovasc Surg. 2023. PMID: 37500053
Decreased mitochondrial respiration in aneurysmal aortas of Fibulin-4 mutant mice is linked to PGC1A regulation.
van der Pluijm I, Burger J, van Heijningen PM, IJpma A, van Vliet N, Milanese C, Schoonderwoerd K, Sluiter W, Ringuette LJ, Dekkers DHW, Que I, Kaijzel EL, Te Riet L, MacFarlane EG, Das D, van der Linden R, Vermeij M, Demmers JA, Mastroberardino PG, Davis EC, Yanagisawa H, Dietz HC, Kanaar R, Essers J. van der Pluijm I, et al. Among authors: macfarlane eg. Cardiovasc Res. 2018 Nov 1;114(13):1776-1793. doi: 10.1093/cvr/cvy150. Cardiovasc Res. 2018. PMID: 29931197 Free PMC article.
TGF-β Family Signaling in Connective Tissue and Skeletal Diseases.
MacFarlane EG, Haupt J, Dietz HC, Shore EM. MacFarlane EG, et al. Cold Spring Harb Perspect Biol. 2017 Nov 1;9(11):a022269. doi: 10.1101/cshperspect.a022269. Cold Spring Harb Perspect Biol. 2017. PMID: 28246187 Free PMC article. Review.
Nonmyocyte ERK1/2 signaling contributes to load-induced cardiomyopathy in Marfan mice.
Rouf R, MacFarlane EG, Takimoto E, Chaudhary R, Nagpal V, Rainer PP, Bindman JG, Gerber EE, Bedja D, Schiefer C, Miller KL, Zhu G, Myers L, Amat-Alarcon N, Lee DI, Koitabashi N, Judge DP, Kass DA, Dietz HC. Rouf R, et al. Among authors: macfarlane eg. JCI Insight. 2017 Aug 3;2(15):e91588. doi: 10.1172/jci.insight.91588. eCollection 2017 Aug 3. JCI Insight. 2017. PMID: 28768908 Free PMC article.
12 results