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Cations but not anions regulate the responsiveness of kainate receptors.
Maclean DM, Wong AY, Fay AM, Bowie D. Maclean DM, et al. J Neurosci. 2011 Feb 9;31(6):2136-44. doi: 10.1523/JNEUROSCI.4314-10.2011. J Neurosci. 2011. PMID: 21307250 Free PMC article.
Na+/Cl- dipole couples agonist binding to kainate receptor activation.
Wong AY, MacLean DM, Bowie D. Wong AY, et al. J Neurosci. 2007 Jun 20;27(25):6800-9. doi: 10.1523/JNEUROSCI.0284-07.2007. J Neurosci. 2007. PMID: 17581967 Free PMC article.
Ancestral reconstruction of the ligand-binding pocket of Family C G protein-coupled receptors.
Kuang D, Yao Y, Maclean D, Wang M, Hampson DR, Chang BS. Kuang D, et al. Proc Natl Acad Sci U S A. 2006 Sep 19;103(38):14050-5. doi: 10.1073/pnas.0604717103. Epub 2006 Sep 11. Proc Natl Acad Sci U S A. 2006. PMID: 16966606 Free PMC article.
Mapping the Conformational Landscape of Glutamate Receptors Using Single Molecule FRET.
MacLean DM, Durham RJ, Jayaraman V. MacLean DM, et al. Trends Neurosci. 2019 Feb;42(2):128-139. doi: 10.1016/j.tins.2018.10.003. Epub 2018 Oct 29. Trends Neurosci. 2019. PMID: 30385052 Free PMC article. Review.
Stargazin promotes closure of the AMPA receptor ligand-binding domain.
MacLean DM, Ramaswamy SS, Du M, Howe JR, Jayaraman V. MacLean DM, et al. J Gen Physiol. 2014 Dec;144(6):503-12. doi: 10.1085/jgp.201411287. J Gen Physiol. 2014. PMID: 25422502 Free PMC article.
Dual Effects of TARP γ-2 on Glutamate Efficacy Can Account for AMPA Receptor Autoinactivation.
Coombs ID, MacLean DM, Jayaraman V, Farrant M, Cull-Candy SG. Coombs ID, et al. Among authors: maclean dm. Cell Rep. 2017 Aug 1;20(5):1123-1135. doi: 10.1016/j.celrep.2017.07.014. Cell Rep. 2017. PMID: 28768197 Free PMC article.
Stargazin Modulation of AMPA Receptors.
Shaikh SA, Dolino DM, Lee G, Chatterjee S, MacLean DM, Flatebo C, Landes CF, Jayaraman V. Shaikh SA, et al. Cell Rep. 2016 Oct 4;17(2):328-335. doi: 10.1016/j.celrep.2016.09.014. Cell Rep. 2016. PMID: 27705782 Free PMC article.
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