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Can we unlock the potential of IGF-1R inhibition in cancer therapy?
King H, Aleksic T, Haluska P, Macaulay VM. King H, et al. Among authors: macaulay vm. Cancer Treat Rev. 2014 Oct;40(9):1096-105. doi: 10.1016/j.ctrv.2014.07.004. Epub 2014 Aug 4. Cancer Treat Rev. 2014. PMID: 25123819 Free PMC article. Review.
Dsh homolog DVL3 mediates resistance to IGFIR inhibition by regulating IGF-RAS signaling.
Gao S, Bajrami I, Verrill C, Kigozi A, Ouaret D, Aleksic T, Asher R, Han C, Allen P, Bailey D, Feller S, Kashima T, Athanasou N, Blay JY, Schmitz S, Machiels JP, Upile N, Jones TM, Thalmann G, Ashraf SQ, Wilding JL, Bodmer WF, Middleton MR, Ashworth A, Lord CJ, Macaulay VM. Gao S, et al. Among authors: macaulay vm. Cancer Res. 2014 Oct 15;74(20):5866-77. doi: 10.1158/0008-5472.CAN-14-0806. Epub 2014 Aug 28. Cancer Res. 2014. PMID: 25168481 Free article.
Durable Response of Spinal Chordoma to Combined Inhibition of IGF-1R and EGFR.
Aleksic T, Browning L, Woodward M, Phillips R, Page S, Henderson S, Athanasou N, Ansorge O, Whitwell D, Pratap S, Hassan AB, Middleton MR, Macaulay VM. Aleksic T, et al. Among authors: macaulay vm. Front Oncol. 2016 May 2;6:98. doi: 10.3389/fonc.2016.00098. eCollection 2016. Front Oncol. 2016. PMID: 27200287 Free PMC article.
IGF-1R associates with adverse outcomes after radical radiotherapy for prostate cancer.
Aleksic T, Verrill C, Bryant RJ, Han C, Worrall AR, Brureau L, Larré S, Higgins GS, Fazal F, Sabbagh A, Haider S, Buffa FM, Cole D, Macaulay VM. Aleksic T, et al. Among authors: macaulay vm. Br J Cancer. 2017 Nov 21;117(11):1600-1606. doi: 10.1038/bjc.2017.337. Epub 2017 Oct 3. Br J Cancer. 2017. PMID: 28972962 Free PMC article.
Nuclear IGF1R Interacts with Regulatory Regions of Chromatin to Promote RNA Polymerase II Recruitment and Gene Expression Associated with Advanced Tumor Stage.
Aleksic T, Gray N, Wu X, Rieunier G, Osher E, Mills J, Verrill C, Bryant RJ, Han C, Hutchinson K, Lambert AG, Kumar R, Hamdy FC, Weyer-Czernilofsky U, Sanderson MP, Bogenrieder T, Taylor S, Macaulay VM. Aleksic T, et al. Among authors: macaulay vm. Cancer Res. 2018 Jul 1;78(13):3497-3509. doi: 10.1158/0008-5472.CAN-17-3498. Epub 2018 May 7. Cancer Res. 2018. PMID: 29735545 Free PMC article.
83 results