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oskar mRNA is localized to the posterior pole of the Drosophila oocyte.
Kim-Ha J, Smith JL, Macdonald PM. Kim-Ha J, et al. Among authors: macdonald pm. Cell. 1991 Jul 12;66(1):23-35. doi: 10.1016/0092-8674(91)90136-m. Cell. 1991. PMID: 2070416
Translational activation of oskar mRNA: reevaluation of the role and importance of a 5' regulatory element [corrected].
Kanke M, Macdonald PM. Kanke M, et al. Among authors: macdonald pm. PLoS One. 2015 May 4;10(5):e0125849. doi: 10.1371/journal.pone.0125849. eCollection 2015. PLoS One. 2015. PMID: 25938537 Free PMC article.
BREs mediate both repression and activation of oskar mRNA translation and act in trans.
Reveal B, Yan N, Snee MJ, Pai CI, Gim Y, Macdonald PM. Reveal B, et al. Among authors: macdonald pm. Dev Cell. 2010 Mar 16;18(3):496-502. doi: 10.1016/j.devcel.2009.12.021. Dev Cell. 2010. PMID: 20230756 Free PMC article.
Two distinct domains of Bruno bind specifically to the oskar mRNA.
Snee M, Benz D, Jen J, Macdonald PM. Snee M, et al. Among authors: macdonald pm. RNA Biol. 2008 Jan-Mar;5(1):1-9. RNA Biol. 2008. PMID: 18388491
A late phase of Oskar accumulation is crucial for posterior patterning of the Drosophila embryo, and is blocked by ectopic expression of Bruno.
Snee MJ, Harrison D, Yan N, Macdonald PM. Snee MJ, et al. Among authors: macdonald pm. Differentiation. 2007 Mar;75(3):246-55. doi: 10.1111/j.1432-0436.2006.00136.x. Differentiation. 2007. PMID: 17359300
Localization-dependent oskar protein accumulation; control after the initiation of translation.
Braat AK, Yan N, Arn E, Harrison D, Macdonald PM. Braat AK, et al. Among authors: macdonald pm. Dev Cell. 2004 Jul;7(1):125-31. doi: 10.1016/j.devcel.2004.06.009. Dev Cell. 2004. PMID: 15239960
Live imaging of nuage and polar granules: evidence against a precursor-product relationship and a novel role for Oskar in stabilization of polar granule components.
Snee MJ, Macdonald PM. Snee MJ, et al. Among authors: macdonald pm. J Cell Sci. 2004 Apr 15;117(Pt 10):2109-20. doi: 10.1242/jcs.01059. J Cell Sci. 2004. PMID: 15090597
Recognition of a bicoid mRNA localization signal by a protein complex containing Swallow, Nod, and RNA binding proteins.
Arn EA, Cha BJ, Theurkauf WE, Macdonald PM. Arn EA, et al. Among authors: macdonald pm. Dev Cell. 2003 Jan;4(1):41-51. doi: 10.1016/s1534-5807(02)00397-0. Dev Cell. 2003. PMID: 12530962
Multiple cis-acting signals, some weak by necessity, collectively direct robust transport of oskar mRNA to the oocyte.
Ryu YH, Kenny A, Gim Y, Snee M, Macdonald PM. Ryu YH, et al. Among authors: macdonald pm. J Cell Sci. 2017 Sep 15;130(18):3060-3071. doi: 10.1242/jcs.202069. Epub 2017 Jul 31. J Cell Sci. 2017. PMID: 28760927 Free PMC article.
RNA localization goes direct.
Arn EA, Macdonald PM. Arn EA, et al. Among authors: macdonald pm. Dev Cell. 2001 Aug;1(2):155-6. doi: 10.1016/s1534-5807(01)00030-2. Dev Cell. 2001. PMID: 11702772 Review.
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