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Design, synthesis and evaluation of monovalent Smac mimetics that bind to the BIR2 domain of the anti-apoptotic protein XIAP.
González-López M, Welsh K, Finlay D, Ardecky RJ, Ganji SR, Su Y, Yuan H, Teriete P, Mace PD, Riedl SJ, Vuori K, Reed JC, Cosford ND. González-López M, et al. Among authors: mace pd. Bioorg Med Chem Lett. 2011 Jul 15;21(14):4332-6. doi: 10.1016/j.bmcl.2011.05.049. Epub 2011 May 24. Bioorg Med Chem Lett. 2011. PMID: 21680182 Free PMC article.
Design, synthesis and evaluation of inhibitor of apoptosis protein (IAP) antagonists that are highly selective for the BIR2 domain of XIAP.
Ardecky RJ, Welsh K, Finlay D, Lee PS, González-López M, Ganji SR, Ravanan P, Mace PD, Riedl SJ, Vuori K, Reed JC, Cosford ND. Ardecky RJ, et al. Among authors: mace pd. Bioorg Med Chem Lett. 2013 Jul 15;23(14):4253-7. doi: 10.1016/j.bmcl.2013.04.096. Epub 2013 May 14. Bioorg Med Chem Lett. 2013. PMID: 23743278 Free PMC article.
Molecular cell death platforms and assemblies.
Mace PD, Riedl SJ. Mace PD, et al. Curr Opin Cell Biol. 2010 Dec;22(6):828-36. doi: 10.1016/j.ceb.2010.08.004. Curr Opin Cell Biol. 2010. PMID: 20817427 Free PMC article. Review.
Caspase enzymology and activation mechanisms.
Mace PD, Riedl SJ, Salvesen GS. Mace PD, et al. Methods Enzymol. 2014;544:161-78. doi: 10.1016/B978-0-12-417158-9.00007-8. Methods Enzymol. 2014. PMID: 24974290
Structural Studies of ERK2 Protein Complexes.
Weijman JF, Riedl SJ, Mace PD. Weijman JF, et al. Among authors: mace pd. Methods Mol Biol. 2017;1487:53-63. doi: 10.1007/978-1-4939-6424-6_4. Methods Mol Biol. 2017. PMID: 27924558
Activation and specificity of human caspase-10.
Wachmann K, Pop C, van Raam BJ, Drag M, Mace PD, Snipas SJ, Zmasek C, Schwarzenbacher R, Salvesen GS, Riedl SJ. Wachmann K, et al. Among authors: mace pd. Biochemistry. 2010 Sep 28;49(38):8307-15. doi: 10.1021/bi100968m. Biochemistry. 2010. PMID: 20795673 Free PMC article.
62 results