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Review article: prebiotics in the gastrointestinal tract.
Macfarlane S, Macfarlane GT, Cummings JH. Macfarlane S, et al. Aliment Pharmacol Ther. 2006 Sep 1;24(5):701-14. doi: 10.1111/j.1365-2036.2006.03042.x. Aliment Pharmacol Ther. 2006. PMID: 16918875 Review.
METHODS: We searched the Science Citation Index with the terms prebiotic, microbiota, gut bacteria, large intestine, mucosa, bowel habit, constipation, diarrhoea, inflammatory bowel disease, Crohn's disease, ulcerative colitis, pouchitis, calcium and cancer, focussing prin …
METHODS: We searched the Science Citation Index with the terms prebiotic, microbiota, gut bacteria, large intestine, mucosa, bowel habit, co …
Synbiotic consumption changes the metabolism and composition of the gut microbiota in older people and modifies inflammatory processes: a randomised, double-blind, placebo-controlled crossover study.
Macfarlane S, Cleary S, Bahrami B, Reynolds N, Macfarlane GT. Macfarlane S, et al. Aliment Pharmacol Ther. 2013 Oct;38(7):804-16. doi: 10.1111/apt.12453. Epub 2013 Aug 20. Aliment Pharmacol Ther. 2013. PMID: 23957631 Clinical Trial.
Oesophageal bacterial biofilm changes in gastro-oesophageal reflux disease, Barrett's and oesophageal carcinoma: association or causality?
Blackett KL, Siddhi SS, Cleary S, Steed H, Miller MH, Macfarlane S, Macfarlane GT, Dillon JF. Blackett KL, et al. Aliment Pharmacol Ther. 2013 Jun;37(11):1084-92. doi: 10.1111/apt.12317. Epub 2013 Apr 22. Aliment Pharmacol Ther. 2013. PMID: 23600758
SUMMARY: Barrett's oesophagus (BO) and gastro-oesophageal reflux disease (GERD) are precursors of oesophageal adenocarcinoma (OAC). ...There was a significant decrease in bacterial counts in the GERD and BO groups for all genera except Campylobacter, which colonised GERD a …
SUMMARY: Barrett's oesophagus (BO) and gastro-oesophageal reflux disease (GERD) are precursors of oesophageal adenocarcinoma (OAC). . …
Induction of cytokine formation by human intestinal bacteria in gut epithelial cell lines.
Bahrami B, Macfarlane S, Macfarlane GT. Bahrami B, et al. J Appl Microbiol. 2011 Jan;110(1):353-63. doi: 10.1111/j.1365-2672.2010.04889.x. Epub 2010 Nov 10. J Appl Microbiol. 2011. PMID: 21070518
The gut microbiota in inflammatory bowel disease.
Macfarlane GT, Blackett KL, Nakayama T, Steed H, Macfarlane S. Macfarlane GT, et al. Curr Pharm Des. 2009;15(13):1528-36. doi: 10.2174/138161209788168146. Curr Pharm Des. 2009. PMID: 19442170 Review.
Crohn's disease and ulcerative colitis are the two principal forms of inflammatory bowel disease (IBD). The root causes of these chronic and acute immunological disorders are unclear, but intestinal microorganisms are known to play a key role in the initiation and maintena …
Crohn's disease and ulcerative colitis are the two principal forms of inflammatory bowel disease (IBD). The root causes of these chro …
Microbial biofilms in the human gastrointestinal tract.
Macfarlane S, Dillon JF. Macfarlane S, et al. J Appl Microbiol. 2007 May;102(5):1187-96. doi: 10.1111/j.1365-2672.2007.03287.x. J Appl Microbiol. 2007. PMID: 17448154 Review.
Mucosal bacteria in ulcerative colitis.
Macfarlane S, Furrie E, Kennedy A, Cummings JH, Macfarlane GT. Macfarlane S, et al. Br J Nutr. 2005 Apr;93 Suppl 1:S67-72. doi: 10.1079/bjn20041347. Br J Nutr. 2005. PMID: 15877898
Bacterial milieu and mucosal bacteria in ulcerative colitis.
Macfarlane GT, Furrie E, Macfarlane S. Macfarlane GT, et al. Novartis Found Symp. 2004;263:57-64; discussion 64-70, 211-8. doi: 10.1002/0470090480.ch5. Novartis Found Symp. 2004. PMID: 15669634 Review.
Synbiotic therapy (Bifidobacterium longum/Synergy 1) initiates resolution of inflammation in patients with active ulcerative colitis: a randomised controlled pilot trial.
Furrie E, Macfarlane S, Kennedy A, Cummings JH, Walsh SV, O'neil DA, Macfarlane GT. Furrie E, et al. Gut. 2005 Feb;54(2):242-9. doi: 10.1136/gut.2004.044834. Gut. 2005. PMID: 15647189 Free PMC article. Clinical Trial.
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