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Anti-angiogenic gene therapy of malignant glioma.
Stratmann A, Machein MR, Plate KH. Stratmann A, et al. Among authors: machein mr. Acta Neurochir Suppl. 1997;68:105-10. doi: 10.1007/978-3-7091-6513-3_20. Acta Neurochir Suppl. 1997. PMID: 9233424 Review.
Differential expression of vascular endothelial growth factor A, its receptors VEGFR-1, -2, and -3 and co-receptors neuropilin-1 and -2 does not predict bevacizumab response in human astrocytomas.
Baumgarten P, Blank AE, Franz K, Hattingen E, Dunst M, Zeiner P, Hoffmann K, Bähr O, Mäder L, Goeppert B, Machein M, Seifert V, Steinbach JP, Plate KH, Harter PN, Mittelbronn M. Baumgarten P, et al. Among authors: machein m. Neuro Oncol. 2016 Feb;18(2):173-83. doi: 10.1093/neuonc/nov288. Epub 2015 Nov 30. Neuro Oncol. 2016. PMID: 26627848 Free PMC article.
Inhibition of solid tumor growth by gene transfer of VEGF receptor-1 mutants.
Heidenreich R, Machein M, Nicolaus A, Hilbig A, Wild C, Clauss M, Plate KH, Breier G. Heidenreich R, et al. Among authors: machein m. Int J Cancer. 2004 Sep 1;111(3):348-57. doi: 10.1002/ijc.20260. Int J Cancer. 2004. PMID: 15221961
Transplanted bone marrow cells preferentially home to the vessels of in situ generated murine tumors rather than of normal organs.
Dwenger A, Rosenthal F, Machein M, Waller C, Spyridonidis A. Dwenger A, et al. Among authors: machein m. Stem Cells. 2004;22(1):86-92. doi: 10.1634/stemcells.22-1-86. Stem Cells. 2004. PMID: 14688394
Angiogenesis in gliomas.
Machein M, de Miguel LS. Machein M, et al. Recent Results Cancer Res. 2009;171:193-215. doi: 10.1007/978-3-540-31206-2_12. Recent Results Cancer Res. 2009. PMID: 19322546 Review.
Lack of evidence for PlGF mediating the tumor resistance after anti-angiogenic therapy in malignant gliomas.
Schneider K, Weyerbrock A, Doostkam S, Plate K, Machein MR. Schneider K, et al. Among authors: machein mr. J Neurooncol. 2015 Jan;121(2):269-78. doi: 10.1007/s11060-014-1647-3. Epub 2014 Nov 5. J Neurooncol. 2015. PMID: 25370707
Endothelial progenitor cells do not contribute to tumor endothelium in primary and metastatic tumors.
Wickersheim A, Kerber M, de Miguel LS, Plate KH, Machein MR. Wickersheim A, et al. Among authors: machein mr. Int J Cancer. 2009 Oct 15;125(8):1771-7. doi: 10.1002/ijc.24605. Int J Cancer. 2009. PMID: 19582874 Free article.
Bone marrow chimera experiments to determine the contribution of hematopoietic stem cells to cerebral angiogenesis.
Machein MR, Plate KH. Machein MR, et al. Methods Mol Biol. 2014;1135:275-88. doi: 10.1007/978-1-4939-0320-7_23. Methods Mol Biol. 2014. PMID: 24510872
Decrease of VEGF-A in myeloid cells attenuates glioma progression and prolongs survival in an experimental glioma model.
Osterberg N, Ferrara N, Vacher J, Gaedicke S, Niedermann G, Weyerbrock A, Doostkam S, Schaefer HE, Plate KH, Machein MR. Osterberg N, et al. Among authors: machein mr. Neuro Oncol. 2016 Jul;18(7):939-49. doi: 10.1093/neuonc/now005. Epub 2016 Mar 6. Neuro Oncol. 2016. PMID: 26951383 Free PMC article.
Flt-1 signaling in macrophages promotes glioma growth in vivo.
Kerber M, Reiss Y, Wickersheim A, Jugold M, Kiessling F, Heil M, Tchaikovski V, Waltenberger J, Shibuya M, Plate KH, Machein MR. Kerber M, et al. Among authors: machein mr. Cancer Res. 2008 Sep 15;68(18):7342-51. doi: 10.1158/0008-5472.CAN-07-6241. Cancer Res. 2008. PMID: 18794121 Free article.
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