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The BAFF/APRIL system: an important player in systemic rheumatic diseases.
Mackay F, Sierro F, Grey ST, Gordon TP. Mackay F, et al. Curr Dir Autoimmun. 2005;8:243-65. doi: 10.1159/000082106. Curr Dir Autoimmun. 2005. PMID: 15564724 Review.
BAFF mediates survival of peripheral immature B lymphocytes.
Batten M, Groom J, Cachero TG, Qian F, Schneider P, Tschopp J, Browning JL, Mackay F. Batten M, et al. Among authors: mackay f. J Exp Med. 2000 Nov 20;192(10):1453-66. doi: 10.1084/jem.192.10.1453. J Exp Med. 2000. PMID: 11085747 Free PMC article.
BAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growth.
Schneider P, MacKay F, Steiner V, Hofmann K, Bodmer JL, Holler N, Ambrose C, Lawton P, Bixler S, Acha-Orbea H, Valmori D, Romero P, Werner-Favre C, Zubler RH, Browning JL, Tschopp J. Schneider P, et al. Among authors: mackay f. J Exp Med. 1999 Jun 7;189(11):1747-56. doi: 10.1084/jem.189.11.1747. J Exp Med. 1999. PMID: 10359578 Free PMC article.
BAFF binds to the tumor necrosis factor receptor-like molecule B cell maturation antigen and is important for maintaining the peripheral B cell population.
Thompson JS, Schneider P, Kalled SL, Wang L, Lefevre EA, Cachero TG, MacKay F, Bixler SA, Zafari M, Liu ZY, Woodcock SA, Qian F, Batten M, Madry C, Richard Y, Benjamin CD, Browning JL, Tsapis A, Tschopp J, Ambrose C. Thompson JS, et al. Among authors: mackay f. J Exp Med. 2000 Jul 3;192(1):129-35. doi: 10.1084/jem.192.1.129. J Exp Med. 2000. PMID: 10880534 Free PMC article.
Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations.
Mackay F, Woodcock SA, Lawton P, Ambrose C, Baetscher M, Schneider P, Tschopp J, Browning JL. Mackay F, et al. J Exp Med. 1999 Dec 6;190(11):1697-710. doi: 10.1084/jem.190.11.1697. J Exp Med. 1999. PMID: 10587360 Free PMC article.
Both the lymphotoxin and tumor necrosis factor pathways are involved in experimental murine models of colitis.
Mackay F, Browning JL, Lawton P, Shah SA, Comiskey M, Bhan AK, Mizoguchi E, Terhorst C, Simpson SJ. Mackay F, et al. Gastroenterology. 1998 Dec;115(6):1464-75. doi: 10.1016/s0016-5085(98)70025-3. Gastroenterology. 1998. PMID: 9834274
Lymphotoxin but not tumor necrosis factor functions to maintain splenic architecture and humoral responsiveness in adult mice.
Mackay F, Majeau GR, Lawton P, Hochman PS, Browning JL. Mackay F, et al. Eur J Immunol. 1997 Aug;27(8):2033-42. doi: 10.1002/eji.1830270830. Eur J Immunol. 1997. PMID: 9295042
Cracking the BAFF code.
Mackay F, Schneider P. Mackay F, et al. Nat Rev Immunol. 2009 Jul;9(7):491-502. doi: 10.1038/nri2572. Nat Rev Immunol. 2009. PMID: 19521398 Review.
Roles of ligands from the TNF superfamily in B cell development, function, and regulation.
Figgett WA, Vincent FB, Saulep-Easton D, Mackay F. Figgett WA, et al. Among authors: mackay f. Semin Immunol. 2014 Jun;26(3):191-202. doi: 10.1016/j.smim.2014.06.001. Epub 2014 Jul 2. Semin Immunol. 2014. PMID: 24996229 Review.
B cells flying solo.
Groom J, Mackay F. Groom J, et al. Among authors: mackay f. Immunol Cell Biol. 2008 Jan;86(1):40-6. doi: 10.1038/sj.icb.7100142. Immunol Cell Biol. 2008. PMID: 18172443 Review.
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