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Harnessing the benefits of PPARβ/δ agonists.
Mackenzie LS, Lione L. Mackenzie LS, et al. Life Sci. 2013 Dec 18;93(25-26):963-7. doi: 10.1016/j.lfs.2013.10.022. Epub 2013 Nov 1. Life Sci. 2013. PMID: 24184294 Review.
Evidence that diclofenac and celecoxib are thyroid hormone receptor beta antagonists.
Zloh M, Perez-Diaz N, Tang L, Patel P, Mackenzie LS. Zloh M, et al. Among authors: mackenzie ls. Life Sci. 2016 Feb 1;146:66-72. doi: 10.1016/j.lfs.2016.01.013. Epub 2016 Jan 11. Life Sci. 2016. PMID: 26792060
The Non-Genomic Effects of the PPARβγ Agonist GW0742 on Streptozotocin Treated Rat Aorta.
Perez-Diaz N, Pushkarsky I, Oweis N, Lione LA, Mackenzie LS. Perez-Diaz N, et al. Among authors: mackenzie ls. Curr Mol Pharmacol. 2018;11(2):149-154. doi: 10.2174/1874467209666161229124356. Curr Mol Pharmacol. 2018. PMID: 28034288
Thyroid Hormone Receptor Antagonists: From Environmental Pollution to Novel Small Molecules.
Mackenzie LS. Mackenzie LS. Vitam Horm. 2018;106:147-162. doi: 10.1016/bs.vh.2017.04.004. Epub 2017 Jun 5. Vitam Horm. 2018. PMID: 29407433 Review.
In silico modelling of prostacyclin and other lipid mediators to nuclear receptors reveal novel thyroid hormone receptor antagonist properties.
Perez Diaz N, Zloh M, Patel P, Mackenzie LS. Perez Diaz N, et al. Among authors: mackenzie ls. Prostaglandins Other Lipid Mediat. 2016 Jan;122:18-27. doi: 10.1016/j.prostaglandins.2015.12.002. Epub 2015 Dec 11. Prostaglandins Other Lipid Mediat. 2016. PMID: 26686607
Linking phospholipase C isoforms with differentiation function in human vascular smooth muscle cells.
Mackenzie LS, Lymn JS, Hughes AD. Mackenzie LS, et al. Biochim Biophys Acta. 2013 Dec;1833(12):3006-3012. doi: 10.1016/j.bbamcr.2013.08.005. Epub 2013 Aug 14. Biochim Biophys Acta. 2013. PMID: 23954266
Selective inhibition of NADPH oxidase reverses the over contraction of diabetic rat aorta.
Rehman AU, Dugic E, Benham C, Lione L, Mackenzie LS. Rehman AU, et al. Among authors: mackenzie ls. Redox Biol. 2014;2:61-4. doi: 10.1016/j.redox.2013.12.002. Epub 2013 Dec 11. Redox Biol. 2014. PMID: 25460721 Free PMC article.
LC-MS/MS confirms that COX-1 drives vascular prostacyclin whilst gene expression pattern reveals non-vascular sites of COX-2 expression.
Kirkby NS, Zaiss AK, Urquhart P, Jiao J, Austin PJ, Al-Yamani M, Lundberg MH, MacKenzie LS, Warner TD, Nicolaou A, Herschman HR, Mitchell JA. Kirkby NS, et al. Among authors: mackenzie ls. PLoS One. 2013 Jul 9;8(7):e69524. doi: 10.1371/journal.pone.0069524. Print 2013. PLoS One. 2013. PMID: 23874970 Free PMC article.
An overview of anti-diabetic plants used in Gabon: Pharmacology and toxicology.
Bading Taika B, Bouckandou M, Souza A, Bourobou Bourobou HP, MacKenzie LS, Lione L. Bading Taika B, et al. Among authors: mackenzie ls. J Ethnopharmacol. 2018 Apr 24;216:203-228. doi: 10.1016/j.jep.2017.12.036. Epub 2018 Jan 2. J Ethnopharmacol. 2018. PMID: 29305175 Review.
A New NO-Releasing Nanoformulation for the Treatment of Pulmonary Arterial Hypertension.
Mohamed NA, Ahmetaj-Shala B, Duluc L, Mackenzie LS, Kirkby NS, Reed DM, Lickiss PD, Davies RP, Freeman GR, Wojciak-Stothard B, Chester AH, El-Sherbiny IM, Mitchell JA, Yacoub MH. Mohamed NA, et al. Among authors: mackenzie ls. J Cardiovasc Transl Res. 2016 Apr;9(2):162-4. doi: 10.1007/s12265-016-9684-2. Epub 2016 Mar 9. J Cardiovasc Transl Res. 2016. PMID: 26960567 Free PMC article.
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