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Methylglyoxal, A Metabolite Increased in Diabetes is Associated with Insulin Resistance, Vascular Dysfunction and Neuropathies.
Shamsaldeen YA, Mackenzie LS, Lione LA, Benham CD. Shamsaldeen YA, et al. Among authors: mackenzie ls. Curr Drug Metab. 2016;17(4):359-67. doi: 10.2174/1389200217666151222155216. Curr Drug Metab. 2016. PMID: 26965039 Review.
The Non-Genomic Effects of the PPARβγ Agonist GW0742 on Streptozotocin Treated Rat Aorta.
Perez-Diaz N, Pushkarsky I, Oweis N, Lione LA, Mackenzie LS. Perez-Diaz N, et al. Among authors: mackenzie ls. Curr Mol Pharmacol. 2018;11(2):149-154. doi: 10.2174/1874467209666161229124356. Curr Mol Pharmacol. 2018. PMID: 28034288
Selective inhibition of NADPH oxidase reverses the over contraction of diabetic rat aorta.
Rehman AU, Dugic E, Benham C, Lione L, Mackenzie LS. Rehman AU, et al. Among authors: mackenzie ls. Redox Biol. 2014;2:61-4. doi: 10.1016/j.redox.2013.12.002. Epub 2013 Dec 11. Redox Biol. 2014. PMID: 25460721 Free PMC article.
An overview of anti-diabetic plants used in Gabon: Pharmacology and toxicology.
Bading Taika B, Bouckandou M, Souza A, Bourobou Bourobou HP, MacKenzie LS, Lione L. Bading Taika B, et al. Among authors: mackenzie ls. J Ethnopharmacol. 2018 Apr 24;216:203-228. doi: 10.1016/j.jep.2017.12.036. Epub 2018 Jan 2. J Ethnopharmacol. 2018. PMID: 29305175 Review.
Evidence that diclofenac and celecoxib are thyroid hormone receptor beta antagonists.
Zloh M, Perez-Diaz N, Tang L, Patel P, Mackenzie LS. Zloh M, et al. Among authors: mackenzie ls. Life Sci. 2016 Feb 1;146:66-72. doi: 10.1016/j.lfs.2016.01.013. Epub 2016 Jan 11. Life Sci. 2016. PMID: 26792060
Reply to letter regarding article, "evidence that links loss of cyclooxygenase-2 with increased asymmetric dimethylarginine: novel explanation of cardiovascular side effects associated with anti-inflammatory drugs".
Ahmetaj-Shala B, Kirkby NS, Knowles R, Al'Yamani M, Mazi S, Wang Z, Tucker AT, Mackenzie LS, Armstrong PC, Nüsing RM, Tomlinson JA, Warner TD, Leiper J, Mitchell JA. Ahmetaj-Shala B, et al. Among authors: mackenzie ls. Circulation. 2015 Oct 27;132(17):e213-4. doi: 10.1161/CIRCULATIONAHA.115.017260. Circulation. 2015. PMID: 26503755 Free article. No abstract available.
Thyroid Hormone Receptor Antagonists: From Environmental Pollution to Novel Small Molecules.
Mackenzie LS. Mackenzie LS. Vitam Horm. 2018;106:147-162. doi: 10.1016/bs.vh.2017.04.004. Epub 2017 Jun 5. Vitam Horm. 2018. PMID: 29407433 Review.
Harnessing the benefits of PPARβ/δ agonists.
Mackenzie LS, Lione L. Mackenzie LS, et al. Life Sci. 2013 Dec 18;93(25-26):963-7. doi: 10.1016/j.lfs.2013.10.022. Epub 2013 Nov 1. Life Sci. 2013. PMID: 24184294 Review.
In silico modelling of prostacyclin and other lipid mediators to nuclear receptors reveal novel thyroid hormone receptor antagonist properties.
Perez Diaz N, Zloh M, Patel P, Mackenzie LS. Perez Diaz N, et al. Among authors: mackenzie ls. Prostaglandins Other Lipid Mediat. 2016 Jan;122:18-27. doi: 10.1016/j.prostaglandins.2015.12.002. Epub 2015 Dec 11. Prostaglandins Other Lipid Mediat. 2016. PMID: 26686607
Aspirin-triggered 15-epi-lipoxin A4 predicts cyclooxygenase-2 in the lungs of LPS-treated mice but not in the circulation: implications for a clinical test.
Kirkby NS, Chan MV, Lundberg MH, Massey KA, Edmands WM, MacKenzie LS, Holmes E, Nicolaou A, Warner TD, Mitchell JA. Kirkby NS, et al. Among authors: mackenzie ls. FASEB J. 2013 Oct;27(10):3938-46. doi: 10.1096/fj.12-215533. Epub 2013 Jun 21. FASEB J. 2013. PMID: 23792301 Free PMC article.
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