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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1941 1
1943 1
1945 4
1946 1
1947 3
1948 1
1949 1
1950 2
1951 2
1952 4
1953 7
1954 6
1955 7
1956 3
1957 5
1958 7
1959 11
1960 15
1961 18
1962 29
1963 28
1964 35
1965 52
1966 50
1967 61
1968 75
1969 93
1970 97
1971 113
1972 125
1973 137
1974 145
1975 303
1976 374
1977 345
1978 291
1979 303
1980 365
1981 372
1982 345
1983 433
1984 484
1985 502
1986 453
1987 496
1988 521
1989 549
1990 566
1991 534
1992 549
1993 567
1994 610
1995 587
1996 653
1997 600
1998 751
1999 711
2000 755
2001 792
2002 849
2003 869
2004 992
2005 1018
2006 1081
2007 1110
2008 1216
2009 1170
2010 1378
2011 1381
2012 1458
2013 1497
2014 1680
2015 1786
2016 1800
2017 1920
2018 2036
2019 2120
2020 2376
2021 2467
2022 2454
2023 2469
2024 2514
2025 2618
2026 575

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51,554 results

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Page 1
Macromolecules and Antibody-Based Drugs.
Su XD, Shuai Y. Su XD, et al. Adv Exp Med Biol. 2020;1248:485-530. doi: 10.1007/978-981-15-3266-5_20. Adv Exp Med Biol. 2020. PMID: 32185723 Review.
Macromolecule drugs particularly antibody drugs are very powerful therapies developing rapidly in the recent 20 years, providing hopes for many patients diagnosed with "incurable" diseases in the past. ...In the last two decades, the proportion of US Food and Drug Administ …
Macromolecule drugs particularly antibody drugs are very powerful therapies developing rapidly in the recent 20 years, providing hope …
Intestinal Permeation Enhancers for Oral Delivery of Macromolecules: A Comparison between Salcaprozate Sodium (SNAC) and Sodium Caprate (C(10)).
Twarog C, Fattah S, Heade J, Maher S, Fattal E, Brayden DJ. Twarog C, et al. Pharmaceutics. 2019 Feb 13;11(2):78. doi: 10.3390/pharmaceutics11020078. Pharmaceutics. 2019. PMID: 30781867 Free PMC article. Review.
Salcaprozate sodium (SNAC) and sodium caprate (C(10)) are two of the most advanced intestinal permeation enhancers (PEs) that have been tested in clinical trials for oral delivery of macromolecules. Their effects on intestinal epithelia were studied for over 30 years, yet …
Salcaprozate sodium (SNAC) and sodium caprate (C(10)) are two of the most advanced intestinal permeation enhancers (PEs) that have been test …
Transdermal Delivery of Macromolecules Using Nano Lipid Carriers.
Kalave S, Chatterjee B, Shah P, Misra A. Kalave S, et al. Curr Pharm Des. 2021;27(42):4330-4340. doi: 10.2174/1381612827666210820095330. Curr Pharm Des. 2021. PMID: 34414868 Review.
Skin's barrier properties prevent the transport of macromolecules at pre-determined therapeutic rates. Notable advancements in macromolecules' transdermal delivery have occurred in recent years. ...Some of these have shown better delivery of macromolecules at …
Skin's barrier properties prevent the transport of macromolecules at pre-determined therapeutic rates. Notable advancements in mac …
Biological macromolecules-based nanoformulation in improving wound healing and bacterial biofilm-associated infection: A review.
Garg SS, Dubey R, Sharma S, Vyas A, Gupta J. Garg SS, et al. Int J Biol Macromol. 2023 Aug 30;247:125636. doi: 10.1016/j.ijbiomac.2023.125636. Epub 2023 Jun 29. Int J Biol Macromol. 2023. PMID: 37392924 Review.
A novel approach to address these concerns is to inhibit biofilm formation using biological-macromolecule based nano-delivery system. Higher drug loading efficiency, sustained drug release, enhanced drug stability, and improved bioavailability are advantages of employing n …
A novel approach to address these concerns is to inhibit biofilm formation using biological-macromolecule based nano-delivery system. …
Locating macromolecules and determining structures inside bacterial cells using electron cryotomography.
Melia CE, Bharat TAM. Melia CE, et al. Biochim Biophys Acta Proteins Proteom. 2018 Sep;1866(9):973-981. doi: 10.1016/j.bbapap.2018.06.003. Epub 2018 Jun 13. Biochim Biophys Acta Proteins Proteom. 2018. PMID: 29908328 Free PMC article. Review.
In this review, we explore the diversity of cryo-ET approaches used for structural and cellular microbiology, with a focus on in situ localization and structure determination of macromolecules. The first section describes strategies employed to locate target macromolecu …
In this review, we explore the diversity of cryo-ET approaches used for structural and cellular microbiology, with a focus on in situ locali …
Entanglements of Macromolecules and Their Influence on Rheological and Mechanical Properties of Polymers.
Pawlak A, Krajenta J. Pawlak A, et al. Molecules. 2024 Jul 20;29(14):3410. doi: 10.3390/molecules29143410. Molecules. 2024. PMID: 39064989 Free PMC article. Review.
Flexible macromolecules easily become entangled with neighboring macromolecules. The resulting network determines many polymer properties, including rheological and mechanical properties. Therefore, a number of experimental and modeling studies were performed to des …
Flexible macromolecules easily become entangled with neighboring macromolecules. The resulting network determines many polymer …
Recent advances in harnessing biological macromolecules for wound management: A review.
Yuan J, Wang S, Yang J, Schneider KH, Xie M, Chen Y, Zheng Z, Wang X, Zhao Z, Yu J, Li G, Kaplan DL. Yuan J, et al. Int J Biol Macromol. 2024 May;266(Pt 1):130989. doi: 10.1016/j.ijbiomac.2024.130989. Epub 2024 Mar 18. Int J Biol Macromol. 2024. PMID: 38508560 Review.
Functional wound dressings (FWDs) prepared from hybrid biological macromolecule-based materials can enhance efficacy of these systems for skin wound management. ...In addition, we highlight the incorporation of biological macromolecules in WDs, the emergence of smar …
Functional wound dressings (FWDs) prepared from hybrid biological macromolecule-based materials can enhance efficacy of these systems …
Local delivery of macromolecules to treat diseases associated with the colon.
Bak A, Ashford M, Brayden DJ. Bak A, et al. Adv Drug Deliv Rev. 2018 Nov-Dec;136-137:2-27. doi: 10.1016/j.addr.2018.10.009. Epub 2018 Oct 22. Adv Drug Deliv Rev. 2018. PMID: 30359631 Review.
We briefly review colonic physiology in relation to the main colon-associated diseases (inflammatory bowel disease, irritable bowel syndrome, infection, and colorectal cancer), along with the impact of colon physiology on dosage form design of macromolecules. We then asses …
We briefly review colonic physiology in relation to the main colon-associated diseases (inflammatory bowel disease, irritable bowel syndrome …
Macromolecules Structural Classification With a 3D Dilated Dense Network in Cryo-Electron Tomography.
Gao S, Han R, Zeng X, Liu Z, Xu M, Zhang F. Gao S, et al. IEEE/ACM Trans Comput Biol Bioinform. 2022 Jan-Feb;19(1):209-219. doi: 10.1109/TCBB.2021.3065986. Epub 2022 Feb 3. IEEE/ACM Trans Comput Biol Bioinform. 2022. PMID: 33729943 Free PMC article.
In STA, to get a high-resolution 3D view of macromolecule structures, diverse macromolecules captured by the cellular tomograms need to be accurately classified. However, due to the poor signal-to-noise-ratio (SNR) and severe ray artifacts in the tomogram, it remain …
In STA, to get a high-resolution 3D view of macromolecule structures, diverse macromolecules captured by the cellular tomogram …
Ion specificities of artificial macromolecules.
Liu L, Kou R, Liu G. Liu L, et al. Soft Matter. 2016 Dec 21;13(1):68-80. doi: 10.1039/c6sm01773h. Soft Matter. 2016. PMID: 27906410 Review.
This review focuses on the ion specificities of artifical macromolecules. Ion specificities are influenced by solvent-mediated indirect ion-macromolecule interactions and also by direct ion-macromolecule interactions. ...For direct ion-macromolecule in …
This review focuses on the ion specificities of artifical macromolecules. Ion specificities are influenced by solvent-mediated indire …
51,554 results
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